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产品图片

货号/SKU
NR-19820
货号/规格
EA
库存与交货期
3-8周
人民币价格
14000
试剂海关审批
A/B级风险物质只能直接使用人购买并持有实验室有效资质,其它询客服确认
国外采购
支持/部分限制一年内购买数量
厂牌
BEI Resources(ATCC)
产品基础信息
生物安全等级建议分类:美国、2
产品描述信息
NR-19820??Leptospira interrogans, M1352, LPS Mutant (Serovar Manilae) (Bacteria)|Leptospira interrogans|M1352, LPS Mutant (Serovar Manilae) |-60°C or colder|B AdlerAcknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Leptospira interrogans, Strain M1352, LPS Mutant (Serovar Manilae), NR-19820."|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
Leptospira interrogans (L. interrogans), strain M1352 (serovar Manilae) is a transposon mutant of wild-type strain L495 created by disruption of a gene of unknown function, Lman_1408, located downstream of a putative sugar pyridoxal-phosphate-dependent aminotransferase and 208 base pairs upstream of a putative rmlC (dTDP-4-dehydrorhamnose 3,5-epimerase), within the lipopolysaccharide (LPS) biosynthesis locus of strain L495.
L. interrogans, strain M1352 (serovar Manilae) has an altered expression of LPS and is highly attenuated in a hamster model of infection. The whole genome shotgun sequence of L. interrogans, strain M1352 (serovar Manilae) is available (GenBank: AHPV00000000).
Each vial contains approximately 0.5 mL of bacterial culture in Ellinghausen-McCullough-Johnson-Harrison (EMJH) Medium supplemented with 2.5% DMSO.
Leptospira interrogans (L. interrogans), strain M1352 (serovar Manilae) is a transposon mutant of wild-type strain L495 created by disruption of a gene of unknown function, Lman_1408, located downstream of a putative sugar pyridoxal-phosphate-dependent aminotransferase and 208 base pairs upstream of a putative rmlC (dTDP-4-dehydrorhamnose 3,5-epimerase), within the lipopolysaccharide (LPS) biosynthesis locus of strain L495.
L. interrogans, strain M1352 (serovar Manilae) has an altered expression of LPS and is highly attenuated in a hamster model of infection. The whole genome shotgun sequence of L. interrogans, strain M1352 (serovar Manilae) is available (GenBank: AHPV00000000).
Each vial contains approximately 0.5 mL of bacterial culture in Ellinghausen-McCullough-Johnson-Harrison (EMJH) Medium supplemented with 2.5% DMSO.
主要内容
此项目的每个订单数量限制为1.此项目每年可订购两次.通过此限制的订单将在发货前发送到NIAID进行批准. leptospira interrogans(L. interrogans),菌株M1352(Serovar Manilae)是一个转座突变体通过破坏未知功能的基因产生的野生型菌株L495, LMAN_1408,位于推定糖吡哆醛磷酸盐依赖性氨基转移酶的下游和推定的 RMLC的上游208碱基对(DTDP-4-DEHYDRORHAMNOSE 3,5-映酶),在脂多糖(LPS)生物合成毒素菌株L495中. l.犯罪者,菌株M1352(Serovar Manilae)具有改变的LPS表达,并且在感染仓鼠模型中高度衰减. l的全基因组霰弹枪序列. interrogans ,菌株M1352(Serovar Manilae)可用(Genbank: ahpv00000000 ). 每个小瓶中含有大约0.5毫升的细菌培养物,尤其是含有2.5%DMSO的2.5%的培养基中的尤利赫森 - McCullough-Johnson-Harrison(EMJH)培养基.
厂牌介绍
BEI Resources 由美国国家过敏和传染病研究所 ( NIAID )成立,旨在为研究 A、B 和 C 类优先病原体、新兴传染病病原体、非病原微生物和其他相关微生物材料提供试剂、工具和信息到研究界。BEI Resources 获取、验证和生产科学家进行基础研究和开发改进的诊断测试、疫苗和疗法所需的试剂。通过将这些功能集中在 BEI Resources 中,可以监控科学界对这些材料的访问和使用,并确保试剂的质量控制。
除了为传染病界提供材料外,BEI Resources 还鼓励和支持研究人员和机构的材料存放。使用 BEI Resources存放材料对研究人员和研究社区有许多优势,包括安全存储、社区访问和分发;同时保护存款人的知识产权。只要有需要,BEI 资源库将作为研究人员的资源进行维护。您在 BEI Resources 的存款是一项有助于未来研究的长期投资。
BEI Resources 自 2003 年起由美国典型培养物保藏中心 (ATCC) 根据合同管理。2016 年 5 月, ATCC获得了一份为期七年的继续管理 BEI Resources的合同。合同范围已扩大到更全面的研究目录材料,包括由其他政府支持的研究项目存放的材料,将提供给生物防御和新兴传染病科学界。真菌、寄生虫、载体和其他相关材料已添加到现有的细菌、病毒和毒素试剂中,涵盖 NIAID A、B 和 C 类优先病原体和 NIAID 指定的新发传染病病原体和生物。
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