NR-3615甲型流感病毒,KilbourneF130:A/NewJersey/11/1976(HA,NA)xA/PuertoRico/8/1934(H1N1),大斑块,重配/突变X-53(CL)-Lp(病毒)
产品图片
货号/SKU
NR-3615
货号/规格
EA
库存与交货期
3-8周
人民币价格
14000
试剂海关审批
A/B级风险物质只能直接使用人购买并持有实验室有效资质,其它询客服确认
国外采购
支持/部分限制一年内购买数量
厂牌
BEI Resources(ATCC)
产品基础信息
生物安全等级建议分类:美国、2
产品描述信息
NR-3615??Influenza A virus , Kilbourne F130: A/New Jersey/11/1976 (HA, NA) x A/Puerto Rico/8/1934 (H1N1), Large Plaque, Reassortant/Mutant X-53 (CL)-Lp(Viruses)|Influenza A virus|Kilbourne F130: A/New Jersey/11/1976 (HA, NA) x A/Puerto Rico/8/1934 (H1N1), Large Plaque, Reassortant/Mutant X-53 (CL)-Lp|-60°C or colder|NIAID/NIHAcknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Kilbourne F130: A/New Jersey/11/1976 (HA, NA) x A/Puerto Rico/8/1934 (H1N1), Large Plaque, Reassortant/Mutant X-53 (CL)-Lp, NR-3615."|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
NR-3615 is a large plaque mutant isolated after multiple passages of X-53 (CL) (Kilbourne F129; BEI Resources NR-3616) in MDCK cells. X-53 (CL) in turn, was derived by limiting dilution cloning in eggs of X-53 (Kilbourne F128; BEI Resources NR-3664), which is a medium yield A/New Jersey/11/1976 (HA, NA) x A/Puerto Rico/8/1934 (H1N1) reassortant. The HA and NA genes of NR-3615 are definitively derived from influenza A/New Jersey/11/1976 (H1N1) (Kilbourne F9, BEI Resources NR-3595), a human isolate recovered during the 1976 swine flu epidemic at Fort Dix, NJ. All other genes are from A/Puerto Rico/8/1934 (H1N1). The derivation and properties of various A/New Jersey/11/1976 (H1N1) reassortants, as well as cloned derivatives, mutants, and re-reassortants thereof, have been described in detail. The HA of NR-3615 is the low yield (L) variant of A/New Jersey/11/1976 (H1N1). The change from H to L phenotype is associated with a single amino acid change in the HA protein.
Each vial contains approximately 1 mL of pooled allantoic fluid from specific pathogen free (SPF) embryonated chicken eggs infected with reassortant/mutant influenza A virus, A/New Jersey/11/1976 (HA, NA) x A/Puerto Rico/8/1934 (H1N1), Large Plaque.
Kilbourne Archive Homepage
Kilbourne/New York Medical College Archive of Influenza Virus Reassortants and Mutants
Kilbourne F130 information
NR-3615 is a large plaque mutant isolated after multiple passages of X-53 (CL) (Kilbourne F129; BEI Resources NR-3616) in MDCK cells. X-53 (CL) in turn, was derived by limiting dilution cloning in eggs of X-53 (Kilbourne F128; BEI Resources NR-3664), which is a medium yield A/New Jersey/11/1976 (HA, NA) x A/Puerto Rico/8/1934 (H1N1) reassortant. The HA and NA genes of NR-3615 are definitively derived from influenza A/New Jersey/11/1976 (H1N1) (Kilbourne F9, BEI Resources NR-3595), a human isolate recovered during the 1976 swine flu epidemic at Fort Dix, NJ. All other genes are from A/Puerto Rico/8/1934 (H1N1). The derivation and properties of various A/New Jersey/11/1976 (H1N1) reassortants, as well as cloned derivatives, mutants, and re-reassortants thereof, have been described in detail. The HA of NR-3615 is the low yield (L) variant of A/New Jersey/11/1976 (H1N1). The change from H to L phenotype is associated with a single amino acid change in the HA protein.
Each vial contains approximately 1 mL of pooled allantoic fluid from specific pathogen free (SPF) embryonated chicken eggs infected with reassortant/mutant influenza A virus, A/New Jersey/11/1976 (HA, NA) x A/Puerto Rico/8/1934 (H1N1), Large Plaque.
Kilbourne Archive Homepage
Kilbourne/New York Medical College Archive of Influenza Virus Reassortants and Mutants
Kilbourne F130 information
主要内容
此项目的每个订单数量限制为1.此商品每年可订购两次.在此限制上订单将在发货前发送至NIAID进行批准. NR-3615是在MDCK细胞中多次传球后分离的大斑块突变体.通过限制X-53(Kilbourne F128; Bei Resource NR-3664)中的卵子稀释克隆来源的X-53(CL)衍生出来,这是一种培养基产量A / New Jersy / 11/1976(HA,NA) X A / Puerto Rico / 8/1934(H1N1)重新排列. NR-3615的HA和Na基因源自甲型A / New Jersy / 11/1976(H1N1)(Kilbourne F9,Bei Resources NR-3595),在1976年猪德克斯堡, nj.所有其他基因来自A / Puerto Rico / 8/1934(H1N1).已经详细描述了各种A / New Jersey / 11/1976(H1N1)反弹的衍生和性质,以及其克隆衍生物,突变体和重新定位. NR-3615的HA是A / NEW JERSEY / 11/1976(H1N1)的低产量(L)变体. H至L表型的变化与HA蛋白的单个氨基酸变化相关. 每个小瓶含有大约1ml的来自特定病原体(SPF)胚胎鸡蛋感染重新排列的鸡蛋突变体流感病毒,A / New Jersey / 11/1976(HA,NA)X A / Puerto Rico / 8/1934(H1N1),大斑块. Kilbourne Archive主页 Kilbourne /纽约医学院归档流感病毒重新排列和突变体 kilbourne f130信息
厂牌介绍
BEI Resources 由美国国家过敏和传染病研究所 ( NIAID )成立,旨在为研究 A、B 和 C 类优先病原体、新兴传染病病原体、非病原微生物和其他相关微生物材料提供试剂、工具和信息到研究界。BEI Resources 获取、验证和生产科学家进行基础研究和开发改进的诊断测试、疫苗和疗法所需的试剂。通过将这些功能集中在 BEI Resources 中,可以监控科学界对这些材料的访问和使用,并确保试剂的质量控制。
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BEI Resources 自 2003 年起由美国典型培养物保藏中心 (ATCC) 根据合同管理。2016 年 5 月, ATCC获得了一份为期七年的继续管理 BEI Resources的合同。合同范围已扩大到更全面的研究目录材料,包括由其他政府支持的研究项目存放的材料,将提供给生物防御和新兴传染病科学界。真菌、寄生虫、载体和其他相关材料已添加到现有的细菌、病毒和毒素试剂中,涵盖 NIAID A、B 和 C 类优先病原体和 NIAID 指定的新发传染病病原体和生物。
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