产品描述信息
NR-52365?? Monoclonal Anti-Influenza A Virus H3 Hemagglutinin (HA), A/Hong Kong/2286/2017 (H3N2), Clone HK17-5 (ascites, Mouse)(Monoclonal Antibodies)|Influenza A virus|Monoclonal Anti-Influenza A Virus H3 Hemagglutinin (HA), A/Hong Kong/2286/2017 (H3N2), Clone HK17-5 (ascites, Mouse)|-20°C to -40°C (Note: Storage at warmer temperatures is not recommended due to a low bioburden.)|St. Jude Children's Research Hospital (CEIRS)Acknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Monoclonal Anti-Influenza A Virus H3 Hemagglutinin (HA), A/Hong Kong/2286/2017 (H3N2), Clone HK17-5 (ascites, Mouse), NR-52365.”|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
Antibody Class: IgG1κ
Mouse monoclonal antibody (clone HK17-5) reactive with the H3 hemagglutinin (HA) of the A/Hong Kong/2286/2017 strain of influenza virus was produced in mouse ascites. Ascites formation was induced by injecting cultured hybridoma cells into the peritoneal cavity of BALB/c mice that had been primed with Incomplete Freund’s adjuvant. The harvested ascites fluid was pooled.
HA is an antigenic glycoprotein found on the envelope of the influenza A virus. This protein binds to cellular receptors on the target cell and allows the influenza A virus to enter via endocytosis and membrane fusion. HA is an important target for drug and vaccine development.
NR-52365 is specific to the H3 HA of influenza virus as determined in serological HI assays. NR-52365 is functional in neutralization, western blot, ELISA, immunoprecipitation and immunohistochemistry.
Each vial contains approximately 0.25 mL mouse ascites fluid, lyophilized.