NR-52362_单克隆抗甲型流感病毒H3血凝素(HA),A/HongKong/2286/2017(H3N2),克隆HK17-2(腹水,小鼠)(单克隆抗体)
产品图片
货号/SKU
NR-52362
货号/规格
EA
库存与交货期
3-8周
人民币价格
14000
试剂海关审批
A/B级风险物质只能直接使用人购买并持有实验室有效资质,其它询客服确认
国外采购
支持/部分限制一年内购买数量
厂牌
BEI Resources(ATCC)
产品基础信息
生物安全等级建议分类:美国、1
产品描述信息
NR-52362?? Monoclonal Anti-Influenza A Virus H3 Hemagglutinin (HA), A/Hong Kong/2286/2017 (H3N2), Clone HK17-2 (ascites, Mouse)(Monoclonal Antibodies)|Influenza A virus|Monoclonal Anti-Influenza A Virus H3 Hemagglutinin (HA), A/Hong Kong/2286/2017 (H3N2), Clone HK17-2 (ascites, Mouse)|-20°C to -40°C (Note: Storage at warmer temperatures is not recommended due to a low bioburden.)|St. Jude Children's Research Hospital (CEIRS)Acknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Monoclonal Anti-Influenza A Virus H3 Hemagglutinin (HA), A/Hong Kong/2286/2017 (H3N2), Clone HK17-2 (ascites, Mouse), NR-52362.”|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
Antibody Class: IgG2bκ
Mouse monoclonal antibody (clone HK17-2) reactive with the H3 hemagglutinin (HA) of the A/Hong Kong/2286/2017 strain of influenza virus was produced in mouse ascites. Ascites formation was induced by injecting cultured hybridoma cells into the peritoneal cavity of BALB/c mice that had been primed with Incomplete Freund’s adjuvant. The harvested ascites fluid was pooled.
HA is an antigenic glycoprotein found on the envelope of the influenza A virus. This protein binds to cellular receptors on the target cell and allows the influenza A virus to enter via endocytosis and membrane fusion. HA is an important target for drug and vaccine development.
NR-52362 is specific to the H3 HA of influenza virus as determined in serological hemagglutinin inhibition (HI) assays. NR-52362 is functional in neutralization, western blot, ELISA, immunoprecipitation and immunohistochemistry.
Each vial contains approximately 0.5 mL mouse ascites fluid, lyophilized.
Antibody Class: IgG2bκ
Mouse monoclonal antibody (clone HK17-2) reactive with the H3 hemagglutinin (HA) of the A/Hong Kong/2286/2017 strain of influenza virus was produced in mouse ascites. Ascites formation was induced by injecting cultured hybridoma cells into the peritoneal cavity of BALB/c mice that had been primed with Incomplete Freund’s adjuvant. The harvested ascites fluid was pooled.
HA is an antigenic glycoprotein found on the envelope of the influenza A virus. This protein binds to cellular receptors on the target cell and allows the influenza A virus to enter via endocytosis and membrane fusion. HA is an important target for drug and vaccine development.
NR-52362 is specific to the H3 HA of influenza virus as determined in serological hemagglutinin inhibition (HI) assays. NR-52362 is functional in neutralization, western blot, ELISA, immunoprecipitation and immunohistochemistry.
Each vial contains approximately 0.5 mL mouse ascites fluid, lyophilized.
主要内容
此项目的每个订单数量限制为1.此商品每年可订购两次.此限制的订单将在发货前发送到NIAID批准.
抗体类:IgG2Bκ
在小鼠腹水中生产与A / HONK / 2286/2017流感病毒的H3 Hemagglutinin(HA)反应的小鼠单克隆抗体(克隆HK17-2).通过将培养的杂交瘤细胞注入伴有不完全弗氏佐剂的Balb / C小鼠的腹膜腔中,诱导腹水形成.合并收获的腹水液.
HA是在流感的血蛋白上发现的抗原糖蛋白.该蛋白质与靶细胞上的细胞受体结合,并允许流感病毒通过内吞作用和膜融合进入. HA是药物和疫苗开发的重要目标.
NR-52362特异于流感病毒的H3公顷,如血清学血凝素抑制(HI)测定中所述. NR-52362是中和,蛋白质印迹,ELISA,免疫沉淀和免疫组化功能.
每个小瓶含有约0.5ml鼠标腹水液,冻干.
厂牌介绍
BEI Resources 由美国国家过敏和传染病研究所 ( NIAID )成立,旨在为研究 A、B 和 C 类优先病原体、新兴传染病病原体、非病原微生物和其他相关微生物材料提供试剂、工具和信息到研究界。BEI Resources 获取、验证和生产科学家进行基础研究和开发改进的诊断测试、疫苗和疗法所需的试剂。通过将这些功能集中在 BEI Resources 中,可以监控科学界对这些材料的访问和使用,并确保试剂的质量控制。
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BEI Resources 自 2003 年起由美国典型培养物保藏中心 (ATCC) 根据合同管理。2016 年 5 月, ATCC获得了一份为期七年的继续管理 BEI Resources的合同。合同范围已扩大到更全面的研究目录材料,包括由其他政府支持的研究项目存放的材料,将提供给生物防御和新兴传染病科学界。真菌、寄生虫、载体和其他相关材料已添加到现有的细菌、病毒和毒素试剂中,涵盖 NIAID A、B 和 C 类优先病原体和 NIAID 指定的新发传染病病原体和生物。
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