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产品图片
货号/SKU
NR-3541
货号/规格
EA
库存与交货期
3-8周
人民币价格
14000
试剂海关审批
A/B级风险物质只能直接使用人购买并持有实验室有效资质，其它询客服确认
国外采购
支持/部分限制一年内购买数量
厂牌
BEI Resources(ATCC)
产品基础信息
生物安全等级建议分类：美国、2
产品描述信息
NR-3541??Influenza A virus, Kilbourne F32: A/NWS/1934 (HA) x A/Beijing/353/1989 (NA) x A/Rockefeller Institute/5/1957 x A/Puerto Rico/8/1934 (H1N2)(Viruses)|Influenza A virus|Kilbourne F32: A/NWS/1934 (HA) x A/Beijing/353/1989 (NA) x A/Rockefeller Institute/5/1957 x A/Puerto Rico/8/1934 (H1N2)|-60°C or colder|NIAID/NIHAcknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Kilbourne F32: A/NWS/1934 (HA) x A/Beijing/353/1989 (NA) x A/Rockefeller Institute/5/1957 x A/Puerto Rico/8/1934 (H1N2), NR-3541."|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
NR-3541 was developed by crossing two previously derived influenza A virus reassortants. X-12 (Kilbourne F82; BEI Resources NR-3545) is A/NWS/1934 (HA) x A/Rockefeller Institute/5/1957 (NA) (H1N2). X-109 is A/Beijing/353/1989 (HA, NA) x A/Puerto Rico/8/1934 (H3N2). Nucleotide sequencing at BEI Resources of a portion of the matrix (M) gene (RNA 7) from NR-3541 indicates that the M gene is derived from A/Puerto Rico/8/1934 (H1N1). The derivation of the five genes encoding the remaining internal proteins and the nonstructural protein has not been determined genotypically.
Like the X-12 parent, NR-3541 is trypsin sensitive - the virus undergoes rapid and selective destruction of hemagglutinin on the virion surface upon treatment with trypsin.
The HA donor of NR-3541 is designated "A/NWS/34" in the Kilbourne Archive. According to Kilbourne, the nomenclature for neurotropic (NWS and WSN) mutants of the original A/Wilson-Smith/1933 (H1N1) human influenza isolate does not usually require the insertion of a date, but if a date is given it should be 1933. Unfortunately, the usage of A/NWS/1933 and A/NWS/1934 is inconsistent, both in the Kilbourne collection and in the literature.
Each vial contains approximately 1 mL of pooled allantoic fluid from specific pathogen free (SPF) embryonated chicken eggs infected with reassortant influenza A virus, A/NWS/1934 (HA) x A/Beijing/353/1989 (NA) x A/Rockefeller Institute/5/1957 x A/Puerto Rico/8/1934 (H1N2).
Kilbourne Archive Homepage
Kilbourne/New York Medical College Archive of Influenza Virus Reassortants and Mutants
Kilbourne F32 information
NR-3541 was developed by crossing two previously derived influenza A virus reassortants. X-12 (Kilbourne F82; BEI Resources NR-3545) is A/NWS/1934 (HA) x A/Rockefeller Institute/5/1957 (NA) (H1N2). X-109 is A/Beijing/353/1989 (HA, NA) x A/Puerto Rico/8/1934 (H3N2). Nucleotide sequencing at BEI Resources of a portion of the matrix (M) gene (RNA 7) from NR-3541 indicates that the M gene is derived from A/Puerto Rico/8/1934 (H1N1). The derivation of the five genes encoding the remaining internal proteins and the nonstructural protein has not been determined genotypically.
Like the X-12 parent, NR-3541 is trypsin sensitive - the virus undergoes rapid and selective destruction of hemagglutinin on the virion surface upon treatment with trypsin.
The HA donor of NR-3541 is designated "A/NWS/34" in the Kilbourne Archive. According to Kilbourne, the nomenclature for neurotropic (NWS and WSN) mutants of the original A/Wilson-Smith/1933 (H1N1) human influenza isolate does not usually require the insertion of a date, but if a date is given it should be 1933. Unfortunately, the usage of A/NWS/1933 and A/NWS/1934 is inconsistent, both in the Kilbourne collection and in the literature.
Each vial contains approximately 1 mL of pooled allantoic fluid from specific pathogen free (SPF) embryonated chicken eggs infected with reassortant influenza A virus, A/NWS/1934 (HA) x A/Beijing/353/1989 (NA) x A/Rockefeller Institute/5/1957 x A/Puerto Rico/8/1934 (H1N2).
Kilbourne Archive Homepage
Kilbourne/New York Medical College Archive of Influenza Virus Reassortants and Mutants
Kilbourne F32 information
主要内容
此项目的每个订单数量限制为1.此商品每年可订购两次.在此限制上订单将在发货前发送至NIAID进行批准. NR-3541是通过穿过两种以前来自衍生的流感的病毒重组而开发的. X-12（Kilbourne F82; Bei Resources NR-3545）是A / NWS / 1934（HA）X A / Rockefeller Institute / 5/1957（NA）（H1N2）. X-109是A /北京/ 353/1989（HA，NA）X A / PUERTO RICO / 8/1934（H3N2）.来自NR-3541的基质（M）基因（RNA 7）的一部分的BEI资源的核苷酸测序表明M基因来自A / Puerto Rico / 8/1934（H1N1）.编码剩余内部蛋白质和非结构蛋白的五种基因的衍生尚未确定基因型.用胰蛋白酶治疗后的病毒赛. NR-3541的HA捐助者在Kilbourne档案中指定了“A / NWS / 34”.根据Kilbourne，原始A / Wilson-Smith / 1933（H1N1）人类流感孤立的神经疗促（NWS和WSN）突变体的命名法通常不需要插入日期，但如果给出日期，则应1933年.不幸的是，A / NWS / 1933和A / NWS / 1934的使用不一致，无论是在Kilbourne收集和文献中. 每个小瓶含有从特定病原体的特定病原体含有大约1毫升汇集的腺体液（SPF）胚胎鸡蛋感染重新排列的流感病毒，A / NWS / 1934（HA）X A / Beijing / 353/153 / 1989（NA）X A / Rockefeller Institute / 5/1957 X A / Puerto Rico / 8/1934 （H1N2）. kilbourne archive主页 Kilbourne /纽约医学院归档流感病毒重新排列和突变体 kilbourne f32信息
厂牌介绍
BEI Resources 由美国国家过敏和传染病研究所 ( NIAID )成立，旨在为研究 A、B 和 C 类优先病原体、新兴传染病病原体、非病原微生物和其他相关微生物材料提供试剂、工具和信息到研究界。BEI Resources 获取、验证和生产科学家进行基础研究和开发改进的诊断测试、疫苗和疗法所需的试剂。通过将这些功能集中在 BEI Resources 中，可以监控科学界对这些材料的访问和使用，并确保试剂的质量控制。
除了为传染病界提供材料外，BEI Resources 还鼓励和支持研究人员和机构的材料存放。使用 BEI Resources存放材料对研究人员和研究社区有许多优势，包括安全存储、社区访问和分发；同时保护存款人的知识产权。只要有需要，BEI 资源库将作为研究人员的资源进行维护。您在 BEI Resources 的存款是一项有助于未来研究的长期投资。
BEI Resources 自 2003 年起由美国典型培养物保藏中心 (ATCC) 根据合同管理。2016 年 5 月， ATCC获得了一份为期七年的继续管理 BEI Resources的合同。合同范围已扩大到更全面的研究目录材料，包括由其他政府支持的研究项目存放的材料，将提供给生物防御和新兴传染病科学界。真菌、寄生虫、载体和其他相关材料已添加到现有的细菌、病毒和毒素试剂中，涵盖 NIAID A、B 和 C 类优先病原体和 NIAID 指定的新发传染病病原体和生物。
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