NR-50255 单克隆抗弓形虫表面抗原 1 蛋白

NR-50255?? Monoclonal Anti-Toxoplasma gondii Surface Antigen 1 Protein, Clone T4 1E5 (produced in vitro)(Monoclonal Antibodies)|Toxoplasma gondii|Monoclonal Anti-Toxoplasma gondii Surface Antigen 1 Protein, Clone T4 1E5 (produced in vitro)|-20°C or colder|JF DubremetzAcknowledgment for publications should read “The following reagent was obtained through BEI Resources, NIAID, NIH: Monoclonal Anti-Toxoplasma gondii Surface Antigen 1 Protein, Clone T4 1E5 (produced in vitro), NR-50255.”|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.Antibody Class: IgG3κMouse monoclonal antibody prepared against the surface antigen 1 (SAG1) protein of Toxoplasma gondii (T. gondii) clone T4 1E5 was purified from the hybridoma supernatant by protein G affinity chromatography. The B cell hybridoma was generated by the fusion of SP2/0 myeloma cells with immunized BALB/c mouse splenocytes. Clone T4 1E5 recognizes the SAG1 protein. SAG1 or P30 protein (~ 30 kDa) is a stage-specific antigen abundant on the surface of both extracellular and intracellular tachyzoites.  It is anchored to the plasma membrane via glycosylphosphatidyl-inositols (GPI) and is one of the most highly-conserved, immunogenic T. gondii antigens. SAG1 is primarily involved in host-cell invasion and receptor binding. Each vial contains approximately 100 ?L of purified monoclonal antibody in PBS, pH 7.4.NR-50255 is reported to react with native SAG1 and to function in immunofluorescence and immunoblot assays.