NR-18139结核分枝杆菌、CDC1551、转座子突变体1522(MT2563、Rv2488c)(突变细菌)
Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
At this time, BEI Resources only maintains seed stock of this item. Once a request is received for this item, it will be added to our production queue. Please allow ample time for distribution lots to be made available.
In 2002, TARGET (Tuberculosis Animal Research and Gene Evaluation Taskforce) was formed to enable the modeling of human tuberculosis in multiple animal species using defined protocols and testing defined mutants of Mycobacterium tuberculosis (M. tuberculosis). In addition to animal modeling activities, a library of intragenic transposon mutants has been created and characterized. M. tuberculosis, transposon mutant 1522 was created by disruption of a probable transcriptional regulatory protein (LuxR family), (MT2563, Rv2488c), of the wild-type strain CDC1551.
Each tube contains a Lowenstein-Jensen (LJ) agar slant that was inoculated with 0.1 mL of bacterial culture and incubated 2 to 6 weeks at 37°C.
TARGET: MT2563
Tuberculist: Rv2488c
ORF Description: Probable transcriptional regulatory protein (LuxR family)
ORF Size: 3342
POI: 43
Additional information is available at Mycobacterium tuberculosis CDC1551 Transposon Mutant Library.
This mutant was developed by Lamichhane, et al. at the Center for Tuberculosis Research, The Johns Hopkins University School of Medicine, PubMed: 12775759.
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