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NR-4??Escherichia coli, H10407 (Serotype O78:H11)(Bacteria)|Escherichia coli|H10407 (Serotype O78:H11)|-60°C or colder|ATCC?Acknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Escherichia coli, Strain H10407, NR-4."| Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment. Escherichia coli (E.coli), strain H10407 was isolated from human feces.Escherichia coli, strain H10407 was deposited at ATCC ? in the early 1980s by Samuel B. Formal, Department of Bacterial Diseases, Walter Reed Army Institute of Research, Washington, DC.The enterotoxigenic Escherichia coli (E. coli; ETEC), strain H10407 was isolated from a patient with diarrhea in Bangladesh. It produces at least two types of virulence factors: 1) colonization factor antigen I (CFA/I), which is responsible for adhesion of bacterial cells to intestinal epithelial cells, and 2) heat-labile (LT) and heat-stable (ST) enterotoxins which cause diarrhea. E. coli H10407 carries three plasmid species: 1) pCS1 (CFA/I+ST+; 95,000 bp), 2) pJY11 (LT+ST+; 65,000 bp), and 3) pTRA1 (65,000 bp), a self-transmissible plasmid which mobilizes pCS1 and pJY11. The gene for another heat-stable enterotoxin (EAST1) has been found in E. coli H10407, sequenced (GenBank: AB042004), and reported to have enterotoxin activity.Each vial contains approximately 0.5 mL of bacterial culture in 0.5X Tryptic Soy Broth supplemented with 10% glycerol.