马库姆试剂|492-2|VMRD|北京沫之东生物技术有限公司

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产品图片

产品英文名称

Equine Coombs Reagent

货号/SKU

492-2

货号/规格

2 ml

库存与交货期

2-4周

人民币价格

询价

人民币价格说明

本商品人民币2024年销售价格正在调整中，请等待更新完毕。

本商品的展示的人民币价格已包含商品本身金额、VAT增值税13%、国际运输运费、国内物流运费、运输保险、以及冷链包装材料（例如液氮罐、泡沫箱、金属桶、蓝冰、湿冰、干冰、蓄冷剂、液氮等）、装卸费、相关资料费、人力支出等一切费用。

本商品的美元价、市场价、零售价、厂商指导价或该商品的曾经展示过的销售价等，并非商品原价，仅供参考。

试剂海关审批

支持海关试剂审批

国外采购

支持

厂牌

VMRD, Inc./USA

品牌

VMRD

产品描述信息

Coombs测试，也称为直接抗球蛋白测试，旨在检测自身免疫性溶血性贫血中发生的免疫介导的红细胞破坏，并且在某些情况下发生感染和肿瘤性疾病。这些疾病中的溶血是由用抗体（IgG，IgM）和/或补体成分（C3）包被的红细胞引起的。涂覆的红细胞在血流中裂解和/或被吞噬细胞除去。 Coombs试剂是山羊制备的IgG，IgM和C3的抗血清。从山羊中获得抗血清后，通过加热使补体失活，然后用洗涤的正常红细胞反复吸收抗血清。这些处理确保Coombs试剂不会与正常红细胞反应。但是，涂有红细胞的红细胞IgG，IgM和/或C3将被包含针对IgG，IgM和C3的抗体的Coombs试剂凝集。

产品安全信息

Two years from date of QC release.

主要内容

The Coombs test, also called direct antiglobulin test, is designed to detect immune-mediated erythrocyte destruction which occurs in autoimmune hemolytic anemias, and in some cases with infections and neoplastic disorders. Hemolysis in these diseases is caused by erythrocytes being coated with antibody (IgG, IgM) and/or complement components (C3). Coated erythrocytes are either lysed in the bloodstream and/or removed by phagocytes. The Coombs reagent is an antiserum to IgG, IgM, and C3 prepared in goats. After obtaining the antiserum from the goat, complement is inactivated by heat and then the antiserum is absorbed repeatedly with washed normal erythrocytes. These treatments ensure that the Coombs reagent will not react with normal erythrocytes. However, erythrocytes that are coated with IgG, IgM, and/or C3 will be agglutinated by the Coombs reagent that contains antibodies to IgG, IgM, and C3.

产品说明书或彩页

https://www.vmrd.com/reagents/detail/equine-coombs-reagent/