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产品图片
货号/SKU
NR-14855
货号/规格
EA
库存与交货期
3-8周
人民币价格
14000
试剂海关审批
A/B级风险物质只能直接使用人购买并持有实验室有效资质,其它询客服确认
国外采购
支持/部分限制一年内购买数量
厂牌
BEI Resources(ATCC)
产品基础信息
生物安全等级建议分类:美国、1
产品描述信息
NR-14855?? Ag85 Complex, Purified Native Protein from Mycobacterium tuberculosis, Strain H37Rv(Proteins)|Mycobacterium tuberculosis|Ag85 Complex, Purified Native Protein from Mycobacterium tuberculosis, Strain H37Rv|-80°C or colder|BEI Resources or NIH - TB Vaccine Testing and Research Materials ContractAcknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Ag85 Complex, Purified Native Protein from Mycobacterium tuberculosis, Strain H37Rv, NR-14855."|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
The Antigen 85 Complex was isolated from Mycobacterium tuberculosis (M. tuberculosis), strain H37Rv culture filtrate proteins and purified. This complex of fibronectin-binding proteins Ag85A (FbpA), Ag85B (FbpB), and Ag85C (FbpC) is the major secreted protein component of M. tuberculosis culture fluids and plays a key role in the pathogenesis of tuberculosis. This protein complex is highly immunogenic and plays a role in cell wall assembly via a mycolyltransferase exchange process. All three purified antigens have shown extensive cross-reactivity and stimulate complement-mediated phagocytosis by host macrophages.
Each vial contains approximately 500 ?g of lyophilized, purified Ag85 complex from Mycobacterium tuberculosis, strain H37Rv in 10 mM ammonium bicarbonate.
Note: NR-14855 is soluble in 100 mM to 500 mM aqueous buffered salt solutions, such as phosphate buffered saline. A 10 mM ammonium bicarbonate solution can also be used.
The Antigen 85 Complex was isolated from Mycobacterium tuberculosis (M. tuberculosis), strain H37Rv culture filtrate proteins and purified. This complex of fibronectin-binding proteins Ag85A (FbpA), Ag85B (FbpB), and Ag85C (FbpC) is the major secreted protein component of M. tuberculosis culture fluids and plays a key role in the pathogenesis of tuberculosis. This protein complex is highly immunogenic and plays a role in cell wall assembly via a mycolyltransferase exchange process. All three purified antigens have shown extensive cross-reactivity and stimulate complement-mediated phagocytosis by host macrophages.
Each vial contains approximately 500 ?g of lyophilized, purified Ag85 complex from Mycobacterium tuberculosis, strain H37Rv in 10 mM ammonium bicarbonate.
Note: NR-14855 is soluble in 100 mM to 500 mM aqueous buffered salt solutions, such as phosphate buffered saline. A 10 mM ammonium bicarbonate solution can also be used.
主要内容
此项目的每个订单数量限制为1.此商品每年可订购两次.此限制的订单将在发货前发送到NIAID批准.
抗原85络合物从结核分枝杆菌(结核分枝杆菌),菌株H37RV培养滤液蛋白质和纯化.这种纤连蛋白结合蛋白AG85A(FBPA),AG85B(FBPB)和AG85C(FBPC)的络合物是 M的主要分泌的蛋白质组分.结核病培养液并在结核病发病机制中发挥关键作用.该蛋白质复合物是高度免疫原性的,并通过巯基转移酶交换过程在细胞壁组件中起作用.所有三种纯化的抗原都显示出广泛的交叉反应性,并通过宿主巨噬细胞刺激补蛋白介导的吞噬作用.
每个小瓶含有大约500μg的冻干,纯化的Ag85复合物,从结核分枝杆菌,菌株H37RV,在10mM碳酸氢铵中.
注意:NR-14855可溶于100mm至500mM的水缓冲盐溶液,例如磷酸盐缓冲盐水.也可以使用10mM碳酸氢铵溶液.
厂牌介绍
BEI Resources 由美国国家过敏和传染病研究所 ( NIAID )成立,旨在为研究 A、B 和 C 类优先病原体、新兴传染病病原体、非病原微生物和其他相关微生物材料提供试剂、工具和信息到研究界。BEI Resources 获取、验证和生产科学家进行基础研究和开发改进的诊断测试、疫苗和疗法所需的试剂。通过将这些功能集中在 BEI Resources 中,可以监控科学界对这些材料的访问和使用,并确保试剂的质量控制。
除了为传染病界提供材料外,BEI Resources 还鼓励和支持研究人员和机构的材料存放。使用 BEI Resources存放材料对研究人员和研究社区有许多优势,包括安全存储、社区访问和分发;同时保护存款人的知识产权。只要有需要,BEI 资源库将作为研究人员的资源进行维护。您在 BEI Resources 的存款是一项有助于未来研究的长期投资。
BEI Resources 自 2003 年起由美国典型培养物保藏中心 (ATCC) 根据合同管理。2016 年 5 月, ATCC获得了一份为期七年的继续管理 BEI Resources的合同。合同范围已扩大到更全面的研究目录材料,包括由其他政府支持的研究项目存放的材料,将提供给生物防御和新兴传染病科学界。真菌、寄生虫、载体和其他相关材料已添加到现有的细菌、病毒和毒素试剂中,涵盖 NIAID A、B 和 C 类优先病原体和 NIAID 指定的新发传染病病原体和生物。
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