NR-50265 单克隆抗弓形虫 ROP2 蛋白

NR-50265?? Monoclonal Anti-Toxoplasma gondii ROP2 Protein, Clone T5 2D1 (produced in vitro)(Monoclonal Antibodies)|Toxoplasma gondii|Monoclonal Anti-Toxoplasma gondii ROP2 Protein, Clone T5 2D1 (produced in vitro)|-20°C or colder|JF DubremetzAcknowledgment for publications should read “The following reagent was obtained through BEI Resources, NIAID, NIH: Monoclonal Anti-Toxoplasma gondii ROP2 Protein, Clone T5 2D1 (produced in vitro), NR-50265.”|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.Antibody Class: IgG1κMouse monoclonal antibody prepared against the rhoptry protein 2 (ROP2) of Toxoplasma gondii clone T5 2D1 was purified from the hybridoma supernatant by protein G affinity chromatography. The B cell hybridoma was generated by the fusion of SP2/0 myeloma cells with immunized BALB/c mouse splenocytes. Clone T5 2D1recognizes the ROP2 protein.  Rhoptry proteins are released concurrent with the formation of the parasitophorous vacuole (PV) and are thought to contribute to both the formation and functional properties of the PV membrane.  ROP2 is the founding member of the ROP2 family of proteins (ROP2, ROP3/ROP8 and ROP4) and mediates the association of PV and host cell mitochondria.  ROP2 is also important for rhoptry biogenesis, parasite invasion and intracellular replication.  Each vial contains approximately 100 ?L of purified monoclonal antibody in PBS (pH 7.4). NR-50265 is reported to react with ROP2 and to function in immunofluorescence and immunoblot assays.