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产品图片

货号/SKU
NR-3460
货号/规格
EA
库存与交货期
3-8周
人民币价格
14000
试剂海关审批
A/B级风险物质只能直接使用人购买并持有实验室有效资质,其它询客服确认
国外采购
支持/部分限制一年内购买数量
厂牌
BEI Resources(ATCC)
产品基础信息
生物安全等级建议分类:美国、2
产品描述信息
NR-3460??Influenza A virus , Kilbourne F35: A/Wilson-Smith/1933 (HA) x A/New Jersey/11/1976 (NA) x A/Puerto Rico/8/1934 (H1N1)(Viruses)|Influenza A virus|Kilbourne F35: A/Wilson-Smith/1933 (HA) x A/New Jersey/11/1976 (NA) x A/Puerto Rico/8/1934 (H1N1)|-60°C or colder|NIAID/NIHAcknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Kilbourne F35: A/Wilson-Smith/1933 (HA) x A/New Jersey/11/1976 (NA) x A/Puerto Rico/8/1934 (H1N1), NR-3460."|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
NR-3460 is an antigenic hybrid reassortant virus that carries the H1 hemagglutinin (HA) of influenza A virus, A/Wilson-Smith/1933 (H1N1) and the neuraminidase (NA) of influenza A virus, A/New Jersey/11/1976 (H1N1), a human isolate recovered during the 1976 swine flu epidemic at Fort Dix, NJ (Kilbourne F9, BEI Resources NR-3595). The parents of this reassortant are influenza A/Wilson-Smith/1933 (H1N1) and the H7N1 reassortant X-54a (Kilbourne F144, BEI Resources NR-3665). The parents of X-54a, in turn, are A/equine/Prague/1/1956 (H7N7) and X-53a (H1N1) (Kilbourne F139, BEI Resources NR-3581). X-53a is a high yield mutant of reassortant X-53 (Kilbourne F128, BEI Resources NR-3664), which is A/New Jersey/11/1976 (HA, NA) x A/Puerto Rico/8/1934 (H1N1). Nucleotide sequencing at BEI Resources of a portion of the matrix (M) gene (RNA 7) from NR-3460 indicates that the M gene is derived from A/Puerto Rico/8/1934 (H1N1). The five genes encoding the remaining internal proteins and the nonstructural protein may be derived from any of A/equine/Prague/1/1956 (H7N7), A/Puerto Rico/8/1934 (H1N1), or from A/Wilson-Smith/1933 (H1N1). The presence of internal and/or nonstructural genes derived from A/New Jersey/11/1976 (H1N1) in NR-3460 is ruled out since X-53 is a 6 + 2 reassortant that carries only the HA and NA genes of the A/New Jersey/11/1976 (H1N1), with all other genes derived from A/Puerto Rico/8/1934 (H1N1).
Each vial contains approximately 1 mL of pooled allantoic fluid from specific pathogen free (SPF) embryonated chicken eggs infected with reassortant influenza A virus, A/Wilson-Smith/1933 (HA) x A/New Jersey/11/1976 (NA) x A/Puerto Rico/8/1934 (H1N1).
Kilbourne Archive Homepage
Kilbourne/New York Medical College Archive of Influenza Virus Reassortants and Mutants
Kilbourne F35 information
NR-3460 is an antigenic hybrid reassortant virus that carries the H1 hemagglutinin (HA) of influenza A virus, A/Wilson-Smith/1933 (H1N1) and the neuraminidase (NA) of influenza A virus, A/New Jersey/11/1976 (H1N1), a human isolate recovered during the 1976 swine flu epidemic at Fort Dix, NJ (Kilbourne F9, BEI Resources NR-3595). The parents of this reassortant are influenza A/Wilson-Smith/1933 (H1N1) and the H7N1 reassortant X-54a (Kilbourne F144, BEI Resources NR-3665). The parents of X-54a, in turn, are A/equine/Prague/1/1956 (H7N7) and X-53a (H1N1) (Kilbourne F139, BEI Resources NR-3581). X-53a is a high yield mutant of reassortant X-53 (Kilbourne F128, BEI Resources NR-3664), which is A/New Jersey/11/1976 (HA, NA) x A/Puerto Rico/8/1934 (H1N1). Nucleotide sequencing at BEI Resources of a portion of the matrix (M) gene (RNA 7) from NR-3460 indicates that the M gene is derived from A/Puerto Rico/8/1934 (H1N1). The five genes encoding the remaining internal proteins and the nonstructural protein may be derived from any of A/equine/Prague/1/1956 (H7N7), A/Puerto Rico/8/1934 (H1N1), or from A/Wilson-Smith/1933 (H1N1). The presence of internal and/or nonstructural genes derived from A/New Jersey/11/1976 (H1N1) in NR-3460 is ruled out since X-53 is a 6 + 2 reassortant that carries only the HA and NA genes of the A/New Jersey/11/1976 (H1N1), with all other genes derived from A/Puerto Rico/8/1934 (H1N1).
Each vial contains approximately 1 mL of pooled allantoic fluid from specific pathogen free (SPF) embryonated chicken eggs infected with reassortant influenza A virus, A/Wilson-Smith/1933 (HA) x A/New Jersey/11/1976 (NA) x A/Puerto Rico/8/1934 (H1N1).
Kilbourne Archive Homepage
Kilbourne/New York Medical College Archive of Influenza Virus Reassortants and Mutants
Kilbourne F35 information
主要内容
此项目的每个订单数量限制为1.此商品每年可订购两次.在此限制上订单将在发货前发送至NIAID进行批准. NR-3460是一种抗原杂交重新排列病毒,其携带流感病毒,A / Wilson-Smith / 1933(H1N1)和流感的神经氨酸酶(NA)的H1 Hemagglutinin(HA)一种病毒,A / New Jersy / 11/1976(H1N1),在1976年猪流感流行病,NJ(Kilbourne F9,Bei Resources NR-3595)中恢复的人类分离物.这种重新排列的父母是流感A / WILSON-SMITH / 1933(H1N1)和H7N1重新分配X-54A(KIKBOURNE F144,BEI资源NR-3665).反过来,X-54a的父母又是一个/马/布拉格/ 1/1956(H7N7)和X-53a(H1N1)(千斤生F139,BEI资源NR-3581). X-53A是重排X-53(Kilbourne F128,Bei Resources NR-3664)的高产量突变体,它是A / New Jersy / 11/1976(HA,NA)X A / Puerto Rico / 8/1934(H1N1 ).来自NR-3460的基质(M)基因(RNA 7)的一部分的BEI资源处的核苷酸测序表明M基因衍生自A / Puerto Rico / 8/1934(H1N1).编码剩余的内部蛋白质和非结构蛋白的五个基因可以衍生自A /马/ Prague / 1/1956(H7N7),A / Puerto Rico / 8/1934(H1N1)或来自A / Wilson-Smith中的任何一种/ 1933(H1N1).从NR-3460中衍生自NR-3460中的内部和/或非结构基因的存在,因为X-53是仅携带A的HA和Na基因的6 + 2重构剂/ New Jersey / 11/1976(H1N1),所有其他基因来自A / Puerto / 8/1934(H1N1). 每个小瓶含有大约1毫升从特定病原体的汇集腺体液( SPF)胚胎鸡蛋感染重新排列的病毒,A / Wilson-Smith / 1933(HA)X A / New Jersy / 11/1976(NA)X A / Puerto Rico / 8/1934(H1N1). kilbourne archive主页 kilbourne /纽约医学院归档流感病毒重新排列和突变体 kilbourne f35信息
厂牌介绍
BEI Resources 由美国国家过敏和传染病研究所 ( NIAID )成立,旨在为研究 A、B 和 C 类优先病原体、新兴传染病病原体、非病原微生物和其他相关微生物材料提供试剂、工具和信息到研究界。BEI Resources 获取、验证和生产科学家进行基础研究和开发改进的诊断测试、疫苗和疗法所需的试剂。通过将这些功能集中在 BEI Resources 中,可以监控科学界对这些材料的访问和使用,并确保试剂的质量控制。
除了为传染病界提供材料外,BEI Resources 还鼓励和支持研究人员和机构的材料存放。使用 BEI Resources存放材料对研究人员和研究社区有许多优势,包括安全存储、社区访问和分发;同时保护存款人的知识产权。只要有需要,BEI 资源库将作为研究人员的资源进行维护。您在 BEI Resources 的存款是一项有助于未来研究的长期投资。
BEI Resources 自 2003 年起由美国典型培养物保藏中心 (ATCC) 根据合同管理。2016 年 5 月, ATCC获得了一份为期七年的继续管理 BEI Resources的合同。合同范围已扩大到更全面的研究目录材料,包括由其他政府支持的研究项目存放的材料,将提供给生物防御和新兴传染病科学界。真菌、寄生虫、载体和其他相关材料已添加到现有的细菌、病毒和毒素试剂中,涵盖 NIAID A、B 和 C 类优先病原体和 NIAID 指定的新发传染病病原体和生物。
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