NR-50552_猪sapovirus,Cowden(适应组织培养)(病毒）
产品图片
货号/SKU
NR-50552
货号/规格
EA
库存与交货期
3-8周
人民币价格
14000
试剂海关审批
A/B级风险物质只能直接使用人购买并持有实验室有效资质，其它询客服确认
国外采购
支持/部分限制一年内购买数量
厂牌
BEI Resources(ATCC)
产品基础信息
生物安全等级建议分类：美国、2
产品描述信息
NR-50552??Porcine sapovirus, Cowden (Tissue Culture Adapted)(Viruses)|Porcine sapovirus|Cowden (Tissue Culture Adapted)|-60°C or colder|LJ SaifAcknowledgment for publications should read “The following reagent was obtained through BEI Resources, NIAID, NIH: Porcine Sapovirus, Cowden (Tissue Culture Adapted), NR-50552.”|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
Porcine sapovirus (PSV), Cowden was isolated in Wayne County, Ohio, USA in 1988 from the large intestinal contents of a 27 day old diarrheic nursing pig, and adapted to growth in cell culture by serial passage in a continuous cell line in the presence of an intestinal content fluid filtrate from uninfected gnotobiotic pigs. The complete genome of tissue culture adapted PSV, Cowden has been sequenced (GenBank: AF182760).
PSV, previously known as porcine enteric calicivirus (PEC), is a member of the family Calciviridae. Calciviridae are small non-enveloped, positive sense, single-stranded RNA viruses classified into five genera including noroviruses and sapoviruses. Noroviruses are the leading cause of nonbacterial gastroenteritis in humans, and sapoviruses are enteric pathogens affecting humans and swine. Sapoviruses are highly diverse and divided into many different genogroups. PSV, Cowden belongs to genogroup III and is one of only a few culturable enteric calciviruses. Bile acids are essential for in vitro propagation of PSV, and may act by a mechanism involving down-regulation of IFN-mediated STAT1 activation. Four amino acid substitutions in the capsid protein (VP1) have been identified as critical for the cell culture adaptation of the virus.
Each vial contains approximately 1 mL of clarified cell lysate and supernatant from Sus scrofa kidney epithelial cells infected with tissue culture adapted PSV, Cowden.
Porcine sapovirus (PSV), Cowden was isolated in Wayne County, Ohio, USA in 1988 from the large intestinal contents of a 27 day old diarrheic nursing pig, and adapted to growth in cell culture by serial passage in a continuous cell line in the presence of an intestinal content fluid filtrate from uninfected gnotobiotic pigs. The complete genome of tissue culture adapted PSV, Cowden has been sequenced (GenBank: AF182760).
PSV, previously known as porcine enteric calicivirus (PEC), is a member of the family Calciviridae. Calciviridae are small non-enveloped, positive sense, single-stranded RNA viruses classified into five genera including noroviruses and sapoviruses. Noroviruses are the leading cause of nonbacterial gastroenteritis in humans, and sapoviruses are enteric pathogens affecting humans and swine. Sapoviruses are highly diverse and divided into many different genogroups. PSV, Cowden belongs to genogroup III and is one of only a few culturable enteric calciviruses. Bile acids are essential for in vitro propagation of PSV, and may act by a mechanism involving down-regulation of IFN-mediated STAT1 activation. Four amino acid substitutions in the capsid protein (VP1) have been identified as critical for the cell culture adaptation of the virus.
Each vial contains approximately 1 mL of clarified cell lysate and supernatant from Sus scrofa kidney epithelial cells infected with tissue culture adapted PSV, Cowden.
主要内容
此项目的每个订单数量限制为1.此商品每年可订购两次.在这一限制下订单将在发货前发送到NIAID进行批准. 猪Sapovirus（PSV），Cowden在俄亥俄州韦恩县孤立于1988年，从大型肠内容物到27日龄腹泻护理猪，并通过连续细胞系中的连续细胞系中的细胞培养中的生长在肠含量流体滤液中，从未感染的骨质猪滤液.组织培养的完整基因组适应了PSV，Cowden已经被测序（GenBank： af182760 ）. psv，以前称为猪肠溶水蛭（pec），是家庭的成员 calciviridae . Calciviridae 是小的非包裹，阳性意义，单链RNA病毒分为五属，包括诺罗病毒和软血病.诺罗病毒是人类中非胃肠炎的主要原因，梭病毒是影响人类和猪的肠道病原体. Sapoviruses高度多样化，分为许多不同的流动组. ＆nbsp; psv，cowden属于Genogroup III，是少数少数培养的肠溶类化合物之一.胆汁酸对于PSV的体外繁殖，并且可以通过涉及IFN介导的STAT1活化的机制作用. Four amino acid substitutions in the capsid protein (VP1) have been identified as critical for the cell culture adaptation of the virus. Each vial contains approximately 1 mL of clarified cell lysate and supernatant from Sus Scrofa 肾上皮细胞感染组织培养适应PSV，Cowden.
厂牌介绍
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BEI Resources 自 2003 年起由美国典型培养物保藏中心 (ATCC) 根据合同管理。2016 年 5 月， ATCC获得了一份为期七年的继续管理 BEI Resources的合同。合同范围已扩大到更全面的研究目录材料，包括由其他政府支持的研究项目存放的材料，将提供给生物防御和新兴传染病科学界。真菌、寄生虫、载体和其他相关材料已添加到现有的细菌、病毒和毒素试剂中，涵盖 NIAID A、B 和 C 类优先病原体和 NIAID 指定的新发传染病病原体和生物。
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