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MW: 185,000
Extinction Coefficient: 1.7
Frozen in 10 mM Tris-HCl, pH 8.0, with 200 mM NaCl and 0.05% NaN3
IgD was first identified in 1965, and like other immunoglobulins, exists as both secreted and membrane forms. Its level in plasma is low with a mean concentration of 30 ug/ml. IgD is present in large quantities on the surface membrane of a majority of human circulating B lymphocytes. IgD enhances humoral immune responses through its induction of IgD-receptor expression on T lymphocytes.
Storage:
Purity: >=95% by SDS-PAGE.
Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.
Lab products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research or further manufacturing use only.
Ref:
Coico RF, Siskind GW, Thorbecke GJ 1988. Immunol. Rev. 105:45.
