NR-49566 单克隆抗豚鼠 (Cavia porcellus) 细胞毒性 T 淋巴细胞相关蛋白 4 胞外结构域

NR-49566?? Monoclonal Anti-Guinea Pig (Cavia porcellus) Cytotoxic T Lymphocyte-Associated Protein-4 Extracellular Domain, Clone GP18.9E7.7D7 (produced in vitro)(Monoclonal Antibodies)|Cavia porcellus|Monoclonal Anti-Guinea Pig (Cavia porcellus) Cytotoxic T Lymphocyte-Associated Protein-4 Extracellular Domain, Clone GP18.9E7.7D7 (produced in vitro)|-20°C or colder|J MukherjeeAcknowledgment for publications should read “The following reagent was obtained through BEI Resources, NIAID, NIH: Monoclonal Anti-Guinea Pig Cytotoxic T Lymphocyte-Associated Protein-4 Extracellular Domain, Clone GP18.9E7.7D7 (produced in vitro), NR-49566.”|Quantity limit per order for this item is 1.  This item can be ordered twice a year.  Orders over this limit will be sent to NIAID for approval before shipment. Antibody Class: IgG2bκMouse monoclonal antibody prepared against a recombinant form of the cytotoxic T lymphocyte-associated protein-4 extracellular domain (CTLA-4 ECD) of guinea pig was purified from clone GP18.9E7.7D7 murine hybridoma supernatant by affinity chromatography. The recombinant CTLA-4 ECD with a C-terminal histidine tag was expressed in yeast. The B cell hybridoma was generated by the fusion of NS0 myeloma cells with immunized mouse splenocytes. CTLA-4 (also known as CD152) is a type I membrane protein belonging to the immunoglobulin superfamily. CTLA-4 exerts an inhibitory signaling effect in T cells and is involved in negative regulation of T-cell activation.Each vial contains approximately 100 ?L of purified monoclonal antibody in 10 mM PBS (pH 7.4) at a concentration of 1 mg per mL. NR-49566 is reactive in ELISA, flow cytometry and western blot analyses.