NR-44233_人类呼吸道合胞病毒,A1998/3-2,从HEp-2细胞(病毒)中纯化
产品图片

货号/SKU
NR-44233
货号/规格
EA
库存与交货期
3-8周
人民币价格
14000
试剂海关审批
A/B级风险物质只能直接使用人购买并持有实验室有效资质,其它询客服确认
国外采购
支持/部分限制一年内购买数量
厂牌
BEI Resources(ATCC)
产品基础信息
生物安全等级建议分类:美国、2
产品描述信息
NR-44233??Human respiratory syncytial virus, A1998/3-2, Purified from HEp-2 Cells(Viruses)|Human respiratory syncytial virus|A1998/3-2, Purified from HEp-2 Cells|-80°C or colder|ML MooreAcknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Human Respiratory Syncytial Virus, A1998/3-2, Purified from HEp-2 Cells, NR-44233."|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
Human respiratory syncytial virus (RSV), A1998/3-2 was isolated from a nasal wash from an infant with RSV bronchiolitis in Nashville, Tennessee, USA on March 2, 1998.
A1998/3-2 is one of six clinical RSV isolates that recently were shown to induce variable disease severity, lung interleukin-13 (IL-13) levels, and gob-5 levels in BALB/cJ mice. IL-13 is a cytokine linked to mucus production and gob-5 is a calcium-activated chloride channel family member implicated in airway inflammation. Compared to mock infection, RSV A1998/3-2 infection led to low levels of gob-5 in lung tissue, no significant elevation in IL-13 expression, and no weight loss in infected mice.
NR-44233 was prepared by inoculation of HEp-2 cells (ATCC ? CCL-23?) with RSV, A1998/3-2. The virus was purified from clarified supernatant by high speed centrifugation.
Each vial contains approximately 0.5 mL of NR-44233 in TBS (0.15 M sodium chloride, 0.05 M Tris-HCl, pH 7.6).
Human respiratory syncytial virus (RSV), A1998/3-2 was isolated from a nasal wash from an infant with RSV bronchiolitis in Nashville, Tennessee, USA on March 2, 1998.
A1998/3-2 is one of six clinical RSV isolates that recently were shown to induce variable disease severity, lung interleukin-13 (IL-13) levels, and gob-5 levels in BALB/cJ mice. IL-13 is a cytokine linked to mucus production and gob-5 is a calcium-activated chloride channel family member implicated in airway inflammation. Compared to mock infection, RSV A1998/3-2 infection led to low levels of gob-5 in lung tissue, no significant elevation in IL-13 expression, and no weight loss in infected mice.
NR-44233 was prepared by inoculation of HEp-2 cells (ATCC ? CCL-23?) with RSV, A1998/3-2. The virus was purified from clarified supernatant by high speed centrifugation.
Each vial contains approximately 0.5 mL of NR-44233 in TBS (0.15 M sodium chloride, 0.05 M Tris-HCl, pH 7.6).
主要内容
此项目的每个订单数量限制为1.此商品每年可订购两次.通过此限制的订单将在发货前发送到NIAID进行批准. 人类呼吸合胞病毒(RSV),A1998 / 3-2从具有RSV支气管炎的婴儿的鼻腔中分离出来纳什维尔,田纳西州,美国1998年3月2日. BALB / CJ小鼠的GOB-5水平. IL-13是与粘液生产连接的细胞因子,GOB-5是钙激活的氯化物通道家族成员,涉及气道炎症.与嘲笑感染相比,RSV A1998 / 3-2感染导致肺组织中的低水平的GOB-5,IL-13表达中没有显着升高,感染小鼠没有减肥. NR-44233通过接种HEP-2细胞(ATCC ? CCL-23 TM)用RSV,A1998 / 3-2进行制备.通过高速离心从澄清的上清液中纯化病毒. 每个小瓶在TBS中含有约0.5ml NR-44233(0.15米氯化钠,0.05M Tris-HCl,pH 7.6).
厂牌介绍
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BEI Resources 自 2003 年起由美国典型培养物保藏中心 (ATCC) 根据合同管理。2016 年 5 月, ATCC获得了一份为期七年的继续管理 BEI Resources的合同。合同范围已扩大到更全面的研究目录材料,包括由其他政府支持的研究项目存放的材料,将提供给生物防御和新兴传染病科学界。真菌、寄生虫、载体和其他相关材料已添加到现有的细菌、病毒和毒素试剂中,涵盖 NIAID A、B 和 C 类优先病原体和 NIAID 指定的新发传染病病原体和生物。
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