NR-15259智人,单克隆抗人干扰素β蛋白,克隆A5(体外生产)(单克隆抗体)
产品图片
货号/SKU
NR-15259
货号/规格
EA
库存与交货期
3-8周
人民币价格
14000
试剂海关审批
A/B级风险物质只能直接使用人购买并持有实验室有效资质,其它询客服确认
国外采购
支持/部分限制一年内购买数量
厂牌
BEI Resources(ATCC)
产品基础信息
生物安全等级建议分类:美国、1
产品描述信息
NR-15259??Homo sapiens, Monoclonal Anti-Human Interferon Beta Protein, Clone A5 (produced in vitro)(Monoclonal Antibodies)|Homo sapiens|Monoclonal Anti-Human Interferon Beta Protein, Clone A5 (produced in vitro)|-20°C or colder|SE GrossbergAcknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Monoclonal Anti-Human Interferon Beta Protein, Clone A5 (produced in vitro), NR-15259."|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
Antibody Class: IgAκ
Mouse monoclonal antibody prepared against a recombinant form of the human interferon beta (IFN-β) protein was purified from clone A5 hybridoma supernatant using a protein-free thiophilic adsorbent. The B cell hybridoma was generated by the fusion of P3X63Ag8.653 myeloma cells with splenocytes from a BALB/c x DBA F1 mouse immunized repeatedly with recombinant human IFN-β protein in adjuvant. The clone A5 antibody is specific for human IFN-β and does not cross-react with IFN-α or IFN-γ.
Each vial of NR-15259 contains approximately 100 ?L of purified monoclonal antibody in PBS.
NR-15259 recognizes recombinant human IFN-? in western blot assays. The clone A5 monoclonal antibody is also reported to function in ELISA and RIA, and to neutralize the anti-viral and anti-proliferative effects of IFN-?. The epitope recognized by the clone A5 antibody has been mapped to the interferon a/? receptor subunit 2 (INFAR-2) binding site of IFN-?.
Antibody Class: IgAκ
Mouse monoclonal antibody prepared against a recombinant form of the human interferon beta (IFN-β) protein was purified from clone A5 hybridoma supernatant using a protein-free thiophilic adsorbent. The B cell hybridoma was generated by the fusion of P3X63Ag8.653 myeloma cells with splenocytes from a BALB/c x DBA F1 mouse immunized repeatedly with recombinant human IFN-β protein in adjuvant. The clone A5 antibody is specific for human IFN-β and does not cross-react with IFN-α or IFN-γ.
Each vial of NR-15259 contains approximately 100 ?L of purified monoclonal antibody in PBS.
NR-15259 recognizes recombinant human IFN-? in western blot assays. The clone A5 monoclonal antibody is also reported to function in ELISA and RIA, and to neutralize the anti-viral and anti-proliferative effects of IFN-?. The epitope recognized by the clone A5 antibody has been mapped to the interferon a/? receptor subunit 2 (INFAR-2) binding site of IFN-?.
主要内容
此项目的每个订单数量限制为1.此商品每年可订购两次.通过此限制的订单将在发货前发送到NIAID进行批准. 抗体类:Igaκ针对人干扰素β(IFN-β)蛋白的重组形式制备的小鼠单克隆抗体使用无蛋白质无蛋白硫酸吸附剂从克隆A5杂交瘤上清液中纯化.通过P3X63AG8.653骨髓瘤细胞的熔化产生B细胞杂交瘤,其中来自BALB / C X DBA F1小鼠的脾细胞与佐剂重组人IFN-β蛋白重复免疫.克隆A5抗体是人IFN-β的特异性,并且不会与IFN-α或IFN-γ交叉反应. 每个小瓶NR-15259在PBS中含有大约100μl纯化的单克隆抗体. NR-15259在Western印迹测定中识别重组人IFN-β.克隆A5单克隆抗体还报告在ELISA和RIA中起作用,并中和IFN-β的抗病毒和抗增殖作用.克隆A5抗体识别的表位已被映射到IFN-β的干扰素A /β受体亚基2(infar-2)结合位点.
厂牌介绍
BEI Resources 由美国国家过敏和传染病研究所 ( NIAID )成立,旨在为研究 A、B 和 C 类优先病原体、新兴传染病病原体、非病原微生物和其他相关微生物材料提供试剂、工具和信息到研究界。BEI Resources 获取、验证和生产科学家进行基础研究和开发改进的诊断测试、疫苗和疗法所需的试剂。通过将这些功能集中在 BEI Resources 中,可以监控科学界对这些材料的访问和使用,并确保试剂的质量控制。
除了为传染病界提供材料外,BEI Resources 还鼓励和支持研究人员和机构的材料存放。使用 BEI Resources存放材料对研究人员和研究社区有许多优势,包括安全存储、社区访问和分发;同时保护存款人的知识产权。只要有需要,BEI 资源库将作为研究人员的资源进行维护。您在 BEI Resources 的存款是一项有助于未来研究的长期投资。
BEI Resources 自 2003 年起由美国典型培养物保藏中心 (ATCC) 根据合同管理。2016 年 5 月, ATCC获得了一份为期七年的继续管理 BEI Resources的合同。合同范围已扩大到更全面的研究目录材料,包括由其他政府支持的研究项目存放的材料,将提供给生物防御和新兴传染病科学界。真菌、寄生虫、载体和其他相关材料已添加到现有的细菌、病毒和毒素试剂中,涵盖 NIAID A、B 和 C 类优先病原体和 NIAID 指定的新发传染病病原体和生物。
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