产品图片
产品别名
货号/SKU
ESL205
货号/规格
100uL
库存与交货期
1-2周
人民币价格
10615
试剂海关审批
使用人负责A/B风险申请资质
国外采购
支持/部分需签MTA
厂牌
Kerafast, Inc.
品牌
产品基础信息
From the laboratory of Abdul Waheed, PhD, St. Louis University.
产品描述信息
Product Type: | Antibody |
Comments: | See "Comments" below for Specifications |
产品安全信息
Türeci Ö, Sahin U, Vollmar E, et al. Human carbonic anhydrase XII: cDNA cloning, expression, and chromosomal localization of a carbonic anhydrase gene that is overexpressed in some renal cell cancers. Proceedings of the National Academy of Sciences of the United States of America. 1998;95(13):7608-7613. Parkkila S, Parkkila A-K, Rajaniemi H, et al. Expression of membrane-associated carbonic anhydrase XIV on neurons and axons in mouse and human brain. Proceedings of the National Academy of Sciences of the United States of America. 2001;98(4):1918-1923. Parkkila, S., Parkkila, A., Juvonen, T., Waheed, A., Sly, W. S., Saarnio, J., Kaunisto, K., Kellokumpu, S. and Rajaniemi, H. (1996), Membrane-bound carbonic anhydrase IV is expressed in the luminal plasma membrane of the human gallbladder epithelium. Hepatology, 24: 11041108. Parkkila S, Rajaniemi H, Parkkila AK, Kivela J, Waheed A, Pastorekova S, Pastorek J, Sly WS. Carbonic anhydrase inhibitor suppresses invasion of renal cancer cells in vitro. Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2220-4. Halmi P, Lehtonen J, Waheed A, Sly WS, Parkkila S. Expression of hypoxia-inducible, membrane-bound carbonic anhydrase isozyme XII in mouse tissues. Anat Rec A Discov Mol Cell Evol Biol. 2004 Mar;277(1):171-7. Kyllönen MS, Parkkila S, Rajaniemi H, Waheed A, Grubb JH, Shah GN, Sly WS, Kaunisto K. Localization of carbonic anhydrase XII to the basolateral membrane of H+-secreting cells of mouse and rat kidney. J Histochem Cytochem. 2003 Sep;51(9):1217-24. Whittington DA, Grubb JH, Waheed A, Shah GN, Sly WS, Christianson DW. Expression, assay, and structure of the extracellular domain of murine carbonic anhydrase XIV: implications for selective inhibition of membrane-associated isozymes. J Biol Chem. 2004 Feb 20;279(8):7223-8. Shah GN, Ulmasov B, Waheed A, Becker T, Makani S, Svichar N, Chesler M, Sly WS. Carbonic anhydrase IV and XIV knockout mice: roles of the respective carbonic anhydrases in buffering the extracellular space in brain. Proc Natl Acad Sci U S A. 2005 Nov 15;102(46):16771-6. Ochrietor JD, Clamp MF, Moroz TP, Grubb JH, Shah GN, Waheed A, Sly WS, Linser PJ. Carbonic anhydrase XIV identified as the membrane CA in mouse retina: strong expression in Müller cells and the RPE. Exp Eye Res. 2005 Oct;81(4):492-500. Shah GN, Rubbelke TS, Hendin J, Nguyen H, Waheed A, Shoemaker JD, Sly WS. Targeted mutagenesis of mitochondrial carbonic anhydrases VA and VB implicates both enzymes in ammonia detoxification and glucose metabolism. Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7423-8. Shah GN, Hewett-Emmett D, Grubb JH, Migas MC, Fleming RE, Waheed A, Sly WS. Mitochondrial carbonic anhydrase CA VB: differences in tissue distribution and pattern of evolution from those of CA VA suggest distinct physiological roles. Goldfarb DS, Sly WS, Waheed A, Charney AN. Acid-base effects on electrolytetransport in CA II-deficient mouse colon. Am J Physiol Gastrointest LiverPhysiol. 2000 Mar;278(3):G409-15. Fleming RE, Parkkila S, Parkkila AK, Rajaniemi H, Waheed A, Sly WS. Carbonicanhydrase IV expression in rat and human gastrointestinal tract regional,cellular, and subcellular localization. J Clin Invest. 1995 Dec;96(6):2907-13. Parkkila AK, Scarim AL, Parkkila S, Waheed A, Corbett JA, Sly WS. Expressionof carbonic anhydrase V in pancreatic beta cells suggests role for mitochondrial carbonic anhydrase in insulin secretion. J Biol Chem. 1998 Sep18;273(38):24620-3.If you publish research with this product, please let us know so we can cite your paper.
主要内容
这些兔IgG多克隆抗体识别人,小鼠或大鼠碳酸酐酶。高灯:识别适用于蛋白质印迹,免疫沉淀和免疫组织化学应用的人,小鼠或大鼠碳酸酐I,II,4,5a,5b,12或14型碳酸酐酶,也称为碳酸酯脱水酶,形成催化二氧化碳快速互连的酶系列和在不存在催化剂的情况下发生的碳酸氢盐和质子。已发现碳酸酐酶在所有哺乳动物组织,植物,藻类和细菌中都是丰富的。有三种主要类碳酸酐,α,哺乳动物,植物酶的β和甲烷产生细菌的γ。这些不同类别的成员分享了很少的序列或结构相似性,但它们具有相同的功能并在活性位点处需要锌离子,因此它们都被分类为金属酶。从Abdul Waheed,Phd,ST的实验室都被分类为金属酶。路易斯大学。
厂牌介绍
关于Kerafast Inc.
Kerafast 是一家位于波士顿的试剂公司,其主要使命是为QuanQiu科学界提供易于使用的独特实验室研究工具。我们的产品组合包括细胞系、抗体、小分子、染料等,其中许多在其他地方无法获得。自 2011 年成立以来,来自全球 190 多个机构的研究人员通过我们的在线平台提供了他们的创新试剂,无需通过传统的材料转让协议流程即可快速获取材料。
我们处理提供实验室的所有销售和运输物流,并从每次销售中返还丰厚的特许权使用费。因此,我们帮助提供实验室节省时间和资源,同时为进一步研究提供额外资金。采购科学家可以更轻松地发现和获取其他地方通常无法获得的独特试剂,同时还可以资助其他研究人员的工作。这创建了一个QuanQiu科学家社区,他们贡献和获取Reagent for the Greater Good,以加速他们自己的研究以及整体科学进步。
2018 年,Kerafast 与Absolute Antibody合并,后者是一家总部位于英国的公司,其愿景是为所有研究人员提供重组抗体技术。此次合并将两家公司聚集在一起,共同致力于改善科学界可用的研究工具的选择。
品牌标识
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