- 1次围观
MW: 230,000
Extinction Coefficient: 1.39
Frozen in 50 mM Tris-HCl, pH 8.0.
Storage:
Bulk Qty Available.
Composed of four identical subunits each with a molecular weight of 58,000. Catalyzes the reaction 2H2O2 to H2O+O2. Catalase, along with the superoxides dismutase and glutathione peroxidase, controls the levels of oxygen-derived free radicals in mammalian cells, and together may function as a somatic oxidant defense.
Ref. Bonaventura, J. et Al. 1972. Arch. Biochem. Biophys. 150, 606; Maehly, A.C. and Chance, B. 1954. Methods Biochem. Anal. 1,357.
Purity: >=95% by SDS-PAGE
Activity: >50,000 units/mg protein. One unit is equal to the amount of enzyme which will decompose one micromole of hydrogen peroxide per minute at 25 degrees Celcius, pH 7.0.
Prepared from whole blood shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.
Lab products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research or further manufacturing use only.
Product Citation:
Xiao, Wusheng, Yueming Zhu, Ehab H. Sarsour, Amanda L. Kalen, Nukhet Aykin-Burns, Douglas R. Spitz, and Prabhat C. Goswami. "Selenoprotein P regulates 1-(4-Chlorophenyl)-benzo-2, 5-quinone induced oxidative stress and toxicity in human keratinocytes."?Free Radical Biology and Medicine?(2013)
