产品图片
货号/SKU
NR-856
货号/规格
EA
库存与交货期
3-8周
人民币价格
14000
试剂海关审批
A/B级风险物质只能直接使用人购买并持有实验室有效资质,其它询客服确认
国外采购
支持/部分限制一年内购买数量
厂牌
BEI Resources(ATCC)
产品基础信息
生物安全等级建议分类:美国、2
产品描述信息
NR-856?? Epsilon Protoxin, from Clostridium perfringens, Strain 34 (Type B)(Toxins)|Clostridium perfringens|Epsilon Protoxin, from Clostridium perfringens, Strain 34 (Type B)|-80°C or colder|AD O'Brien, JF SinclairAcknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Epsilon Protoxin, from Clostridium perfringens, Strain 34 (Type B), NR-856."|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
Epsilon protoxin was purified from culture supernatants of Clostridium perfringens (C. perfringens), strain 34 (type B) (ATCC ? 3626?). The protein is suitable for western blots or can be treated with trypsin to generate the active toxin for cytotoxicity assays.
Epsilon toxin is produced by strains of C. perfringens that inhabit the intestinal tract of sheep and lambs. Intoxication results in enterotoxemia and neurological disorders and is usually fatal in certain livestock. The sequence of the gene for the epsilon toxin precursor protein has been reported (GenBank: M95206). The structure of epsilon protoxin has been solved (PDB: 1UYJ).
NR-856 reacts with polyclonal IgG antibody produced by immunization of rabbits with peptides that correspond to distinct internal regions of the full-length epsilon toxin (BEI Resources NR-865).
Each vial of NR-856 contains approximately 0.25 mg of epsilon protoxin suspended in 10 mM phosphate buffer (pH 7.4).
For information about toxin amounts excluded from CDC Select Agent regulations, click here.
Epsilon protoxin was purified from culture supernatants of Clostridium perfringens (C. perfringens), strain 34 (type B) (ATCC ? 3626?). The protein is suitable for western blots or can be treated with trypsin to generate the active toxin for cytotoxicity assays.
Epsilon toxin is produced by strains of C. perfringens that inhabit the intestinal tract of sheep and lambs. Intoxication results in enterotoxemia and neurological disorders and is usually fatal in certain livestock. The sequence of the gene for the epsilon toxin precursor protein has been reported (GenBank: M95206). The structure of epsilon protoxin has been solved (PDB: 1UYJ).
NR-856 reacts with polyclonal IgG antibody produced by immunization of rabbits with peptides that correspond to distinct internal regions of the full-length epsilon toxin (BEI Resources NR-865).
Each vial of NR-856 contains approximately 0.25 mg of epsilon protoxin suspended in 10 mM phosphate buffer (pH 7.4).
For information about toxin amounts excluded from CDC Select Agent regulations, click here.
主要内容
此项目的每个订单数量限制为1.此商品每年可订购两次.此限制的订单将在发货前发送到NIAID批准.
从蛋白质(C. perfringens)的培养上清液中纯化Epsilon protoxin(C. perfringens),菌株34(B)(ATCC ? 3626?).该蛋白质适用于蛋白质印迹,或者可以用胰蛋白酶处理,以产生用于细胞毒性测定的活性毒素.
Epsilon毒素是通过 c的菌株产生的.完全居住在绵羊和羊羔的肠道.中毒导致肠毒性和神经系统疾病,通常在某些牲畜中致命.报道了ε毒素前体蛋白的基因序列(Genbank:M95206). epsilon protoxin的结构已解决(PDB:1UYJ).
NR-856与通过对应于全长ε毒素的不同内部区域的兔免疫兔产生的多克隆IgG抗体反应(Bei资源NR-865).
每个小瓶NR-856含有约0.25mg悬浮在10mM磷酸盐缓冲液(pH 7.4)中的ε-氧锆状原毒素.
有关从CDC中排除的毒素金额的信息,请选择代理规则,点击这里.
厂牌介绍
BEI Resources 由美国国家过敏和传染病研究所 ( NIAID )成立,旨在为研究 A、B 和 C 类优先病原体、新兴传染病病原体、非病原微生物和其他相关微生物材料提供试剂、工具和信息到研究界。BEI Resources 获取、验证和生产科学家进行基础研究和开发改进的诊断测试、疫苗和疗法所需的试剂。通过将这些功能集中在 BEI Resources 中,可以监控科学界对这些材料的访问和使用,并确保试剂的质量控制。
除了为传染病界提供材料外,BEI Resources 还鼓励和支持研究人员和机构的材料存放。使用 BEI Resources存放材料对研究人员和研究社区有许多优势,包括安全存储、社区访问和分发;同时保护存款人的知识产权。只要有需要,BEI 资源库将作为研究人员的资源进行维护。您在 BEI Resources 的存款是一项有助于未来研究的长期投资。
BEI Resources 自 2003 年起由美国典型培养物保藏中心 (ATCC) 根据合同管理。2016 年 5 月, ATCC获得了一份为期七年的继续管理 BEI Resources的合同。合同范围已扩大到更全面的研究目录材料,包括由其他政府支持的研究项目存放的材料,将提供给生物防御和新兴传染病科学界。真菌、寄生虫、载体和其他相关材料已添加到现有的细菌、病毒和毒素试剂中,涵盖 NIAID A、B 和 C 类优先病原体和 NIAID 指定的新发传染病病原体和生物。
品牌标识
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