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产品图片

货号/SKU
NR-4673
货号/规格
EA
库存与交货期
3-8周
人民币价格
14000
试剂海关审批
A/B级风险物质只能直接使用人购买并持有实验室有效资质,其它询客服确认
国外采购
支持/部分限制一年内购买数量
厂牌
BEI Resources(ATCC)
产品基础信息
生物安全等级建议分类:美国、1
产品描述信息
NR-4673?? Epsilon Toxoid (Chemically Inactivated Epsilon Toxin) from Clostridium perfringens(Toxins)|Clostridium perfringens|Epsilon Toxoid (Chemically Inactivated Epsilon Toxin) from Clostridium perfringens|-20°C or colder (Note: For long term storage, store at -80°C or colder.)|AD O'Brien, JF SinclairAcknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Epsilon Toxoid (Chemically Inactivated Epsilon Toxin) from Clostridium perfringens, NR-4673."|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
NR-4673 is a preparation of epsilon toxin which was purified from culture supernatants of Clostridium perfringens (C. perfringens) and inactivated by treatment with 1% formaldehyde. Unreacted formaldehyde was removed by dialysis against PBS.
Epsilon toxin is produced by strains of C. perfringens that inhabit the intestinal tract of sheep and lambs. Intoxication results in enterotoxemia and neurological disorders and is usually fatal in certain livestock. The sequence of the gene for the epsilon toxin precursor protein has been reported (GenBank: M95206 and M80837). The structure of epsilon protoxin has been solved (PDB: 1UYJ).
Each vial of NR-4673 contains approximately 0.1 mg of epsilon toxoid in PBS.
NR-4673 is reactive with polyclonal immunoglobulin G produced by immunization of rabbits with peptides that correspond to distinct internal regions of the full-length epsilon toxin (BEI Resources NR-865) on western blots.
NR-4673 is a preparation of epsilon toxin which was purified from culture supernatants of Clostridium perfringens (C. perfringens) and inactivated by treatment with 1% formaldehyde. Unreacted formaldehyde was removed by dialysis against PBS.
Epsilon toxin is produced by strains of C. perfringens that inhabit the intestinal tract of sheep and lambs. Intoxication results in enterotoxemia and neurological disorders and is usually fatal in certain livestock. The sequence of the gene for the epsilon toxin precursor protein has been reported (GenBank: M95206 and M80837). The structure of epsilon protoxin has been solved (PDB: 1UYJ).
Each vial of NR-4673 contains approximately 0.1 mg of epsilon toxoid in PBS.
NR-4673 is reactive with polyclonal immunoglobulin G produced by immunization of rabbits with peptides that correspond to distinct internal regions of the full-length epsilon toxin (BEI Resources NR-865) on western blots.
主要内容
此项目的每个订单数量限制为1.此商品每年可订购两次.此限制的订单将在发货前发送到NIAID进行批准. NR-4673是ε-4673的制备,其纯化从梭菌(C. perfringens)的培养上清液中纯化通过用1%甲醛处理灭活并灭活.通过对PBS的透析除去未反应的甲醛. ε毒素是通过 c的菌株产生的.完全居住在绵羊和羊羔的肠道.中毒导致肠毒性和神经系统疾病,通常在某些牲畜中致命.据报道了ε毒素前体蛋白的基因序列(Genbank:M95206和M80837). epsilon protoxin的结构已经解决了(PDB:1UYJ). NR-4673与多克隆免疫球蛋白是反应性的通过用肽免疫兔产生的G产生,所述兔对应于蛋白质印迹的全长ε毒素(BEI资源NR-865)的不同内部区域.
厂牌介绍
BEI Resources 由美国国家过敏和传染病研究所 ( NIAID )成立,旨在为研究 A、B 和 C 类优先病原体、新兴传染病病原体、非病原微生物和其他相关微生物材料提供试剂、工具和信息到研究界。BEI Resources 获取、验证和生产科学家进行基础研究和开发改进的诊断测试、疫苗和疗法所需的试剂。通过将这些功能集中在 BEI Resources 中,可以监控科学界对这些材料的访问和使用,并确保试剂的质量控制。
除了为传染病界提供材料外,BEI Resources 还鼓励和支持研究人员和机构的材料存放。使用 BEI Resources存放材料对研究人员和研究社区有许多优势,包括安全存储、社区访问和分发;同时保护存款人的知识产权。只要有需要,BEI 资源库将作为研究人员的资源进行维护。您在 BEI Resources 的存款是一项有助于未来研究的长期投资。
BEI Resources 自 2003 年起由美国典型培养物保藏中心 (ATCC) 根据合同管理。2016 年 5 月, ATCC获得了一份为期七年的继续管理 BEI Resources的合同。合同范围已扩大到更全面的研究目录材料,包括由其他政府支持的研究项目存放的材料,将提供给生物防御和新兴传染病科学界。真菌、寄生虫、载体和其他相关材料已添加到现有的细菌、病毒和毒素试剂中,涵盖 NIAID A、B 和 C 类优先病原体和 NIAID 指定的新发传染病病原体和生物。
品牌标识

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