NR-15513单克隆抗登革病毒3型包膜蛋白,克隆E4(体外生产)(单克隆抗体)
产品图片
货号/SKU
NR-15513
货号/规格
EA
库存与交货期
3-8周
人民币价格
14000
试剂海关审批
A/B级风险物质只能直接使用人购买并持有实验室有效资质,其它询客服确认
国外采购
支持/部分限制一年内购买数量
厂牌
BEI Resources(ATCC)
产品基础信息
生物安全等级建议分类:美国、1
产品描述信息
NR-15513?? Monoclonal Anti-Dengue Virus Type 3 Envelope Protein, Clone E4 (produced in vitro)(Monoclonal Antibodies)|Dengue virus type 3|Monoclonal Anti-Dengue Virus Type 3 Envelope Protein, Clone E4 (produced in vitro)|-20°C or colder|MS DiamondAcknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Monoclonal Anti-Dengue Virus Type 3 Envelope Protein, Clone E4 (produced in vitro), NR-15513."|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
Antibody Class: IgG1κ
Mouse monoclonal antibody prepared against the envelope protein of dengue virus type 3 (DEN-3) was purified from clone E4 hybridoma supernatant by protein G affinity chromatography. The B cell hybridoma was generated by the fusion of P3X63Ag8.653 myeloma cells with immunized mouse splenocytes. The clone E4 antibody is reported to bind to domain I/II (DI/II) in the envelope protein.
Each vial of NR-15513 contains approximately 0.1 mL of purified monoclonal antibody in PBS.
NR-15513 is reported to be type-specific, non-neutralizing, and to react with DEN-3 DI/II expressed on yeast cells. Lot 59559735 was released without confirmation of functional activity. Lot 61723995 has been shown to react with DEN-3, MK-594-87 (BEI Resources NR-3799) in indirect immunofluorescence assays and ELISA.
Antibody Class: IgG1κ
Mouse monoclonal antibody prepared against the envelope protein of dengue virus type 3 (DEN-3) was purified from clone E4 hybridoma supernatant by protein G affinity chromatography. The B cell hybridoma was generated by the fusion of P3X63Ag8.653 myeloma cells with immunized mouse splenocytes. The clone E4 antibody is reported to bind to domain I/II (DI/II) in the envelope protein.
Each vial of NR-15513 contains approximately 0.1 mL of purified monoclonal antibody in PBS.
NR-15513 is reported to be type-specific, non-neutralizing, and to react with DEN-3 DI/II expressed on yeast cells. Lot 59559735 was released without confirmation of functional activity. Lot 61723995 has been shown to react with DEN-3, MK-594-87 (BEI Resources NR-3799) in indirect immunofluorescence assays and ELISA.
主要内容
此项目的每个订单数量限制为1.此商品每年可订购两次.在此限制上订单将在发货前发送到NIAID进行批准. 抗体类:IgG1κ针对登革热病毒3(DEN-3)的包络蛋白制备的小鼠单克隆抗体是通过蛋白G亲和层析从克隆E4杂交瘤上清液中纯化.通过免疫小鼠脾细胞的P3X63AG8.653骨髓瘤细胞的融合产生B细胞杂交瘤.据报道克隆E4抗体在包膜蛋白中结合结构域I / II(DI / II). 每个小瓶在PBS中含有约0.1ml纯化的单克隆抗体. NR-15513是特异性的,不中和,并与在酵母细胞上表达的DEN-3 DI / II反应.批量释放了59559735,无需确认功能活动.已经显示了Lot 61723995在间接免疫荧光测定和ELISA中与DEN-3,MK-594-87(BEI资源NR-3799)反应.
厂牌介绍
BEI Resources 由美国国家过敏和传染病研究所 ( NIAID )成立,旨在为研究 A、B 和 C 类优先病原体、新兴传染病病原体、非病原微生物和其他相关微生物材料提供试剂、工具和信息到研究界。BEI Resources 获取、验证和生产科学家进行基础研究和开发改进的诊断测试、疫苗和疗法所需的试剂。通过将这些功能集中在 BEI Resources 中,可以监控科学界对这些材料的访问和使用,并确保试剂的质量控制。
除了为传染病界提供材料外,BEI Resources 还鼓励和支持研究人员和机构的材料存放。使用 BEI Resources存放材料对研究人员和研究社区有许多优势,包括安全存储、社区访问和分发;同时保护存款人的知识产权。只要有需要,BEI 资源库将作为研究人员的资源进行维护。您在 BEI Resources 的存款是一项有助于未来研究的长期投资。
BEI Resources 自 2003 年起由美国典型培养物保藏中心 (ATCC) 根据合同管理。2016 年 5 月, ATCC获得了一份为期七年的继续管理 BEI Resources的合同。合同范围已扩大到更全面的研究目录材料,包括由其他政府支持的研究项目存放的材料,将提供给生物防御和新兴传染病科学界。真菌、寄生虫、载体和其他相关材料已添加到现有的细菌、病毒和毒素试剂中,涵盖 NIAID A、B 和 C 类优先病原体和 NIAID 指定的新发传染病病原体和生物。
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