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MW: 550,000
Lyophilized from 10 mM Na deoxycholate, pH 10.0, with 50 mM Na2CO3 and 50 mM NaCl.
Storage:
Buy Purified Native Human Apolipoprotein B (ApoB), Human Plasma.
Bulk Qty Available.
Apolipoprotein B is the dominant protein constituent of LDL. The concentration of Apo B in normal plasma is 90 mg per 100 ml. Apo B is thought to stabilize lipid emulsions, serve as a cofactor and modulator of enzymatic reactions, manage export of lipids out of cells and direct lipids to target organs. Apo B levels are positively correlated with the risk of coronary disease. Apo B levels may be a more sensitive predictor of cardiovascular risk than LDL levels and do not involve fasting for accurate measurement.
Two forms of Apo B exist: Apo B-100 and Apo B-48. The first is found in VLDL and LDL and is produced by the liver. The second is found in chylomicrons and originates in the intestine.
Ref: Guevara, J.G et al. 1999. Journal of Protein Chemistry. 18, 845.
Purity: >=95% by SDS-PAGE; Single arc by IEP against whole human serum.
Prepared from fresh, non-frozen plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Lab products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research or further manufacturing use only.
