- 7 次围观
Species Reactivity: Human
Host: Rabbit
Immunogen Source: Human Neutrophil
Form: Ig Fraction (Standard Antisera) obtained by ammonium sulfate precipitation.
Buffer: phosphate buffered saline with 0.05% NaN3 as a preservative
Storage: +2 to 8°C
Protein Concentration: Lot Specific
Working Dilution: >1:4000 by indirect ELISA.
Western Blot: At a 1:1000 dilution, reacts to 0.3 ug purified antigen when run under non-reducing conditions. Does not show a reaction when antigen is run under reducing conditions.
IEP: Single arc against human neutrophil granule extract and human neutrophil elastase.
The Elastase immunogen used to prepare this antibody was purified in the Lab laboratory. It is a native protein, whole molecule, isolated from human neutrophils.
PLEASE NOTE: This product is a laboratory reagent and is not to be administered to humans or used for any drug purpose. For research use only.
References:
Skrzeczynska-Moncznik J, et al. Eosinophils regulate interferon alpha production in plasmacytoid dendritic cells stimulated with components of neutrophil extracellular traps. J Interferon Cytokine Res. 2017 Mar;37(3):119-128. doi: 10.1089/jir.2016.0036. Epub 2017 Feb 10.
Zabieglo K, et al. The inhibitory effect of secretory leukocyte protease inhibitor (SLPI) on formation of neutrophil extracellular traps. J Leukoc Biol. 2015 Jul;98(1):99-106. doi: 10.1189/jlb.4AB1114-543R. Epub 2015 Apr 27.
