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产品图片

货号/SKU
NR-53953
货号/规格
EA
库存与交货期
3-8周
人民币价格
14000
试剂海关审批
A/B级风险物质只能直接使用人购买并持有实验室有效资质,其它询客服确认
国外采购
支持/部分限制一年内购买数量
厂牌
BEI Resources(ATCC)
产品基础信息
生物安全等级建议分类:美国、3
产品描述信息
NR-53953??SARS-Related Coronavirus 2, Isolate hCoV-19/Denmark/DCGC-3024/2020 (Viruses)|SARS-Related Coronavirus 2|Isolate hCoV-19/Denmark/DCGC-3024/2020 |-60°C or colder|A Fomsgaard, Public Health EnglandAcknowledgment for publications should read “The following reagent was obtained through BEI Resources, NIAID, NIH: SARS-Related Coronavirus 2, Isolate hCoV-19/Denmark/DCGC-3024/2020, NR-53953, contributed by Anders Fomsgaard and Public Health England.”|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), isolate hCoV-19/Denmark/DCGC-3024/2020 (also referred to as SARS-CoV-2, isolate hCoV-19/hu/DK/CL-5/1; Please note that the depositor’s original strain designation was used on the product label.) was isolated from a human who was exposed to a COVID-19 infected mink in Northern Jutland, Denmark on October 5, 2020.
Note: Genome sequence information is provided on the Certificate of Analysis and includes an analysis of all sequence variations observed for each lot.
Under the nomenclature system introduced by GISAID (Global Initiative on Sharing All Influenza Data), SARS-CoV-2, isolate hCoV-19/Denmark/DCGC-3024/2020 is assigned lineage B.1.1.298 and GISAID clade GR using Phylogenetic Assignment of Named Global Outbreak LINeages (PANGOLIN) tool. The complete genome of SARS-CoV-2, isolate hCoV-19/Denmark/DCGC-3024/2020 has been sequenced (GISAID: EPI_ISL_616802). The following mutations are present in the clinical isolate: Spike D614G, Spike H69del, Spike I692V, Spike M1229I, Spike V70del, Spike Y453F, N (Nucleocapsid protein) G204R, N R203K, N S194L, NSP1 (Non-structural protein 1) M85del, NSP3 (Non-structural protein 3) H182Y, NSP3 N1263del, NSP12 (Non-structural protein 12) P323L, NSP12 T739I, NSP15 (Non-structural protein 15) T112I. SARS-CoV-2, isolate hCoV-19/Denmark/DCGC-3024/2020 is a mink-associated SARS-CoV-2 Cluster 5 (also referred to as ΔFVI-spike) virus defined by the following Spike mutations: H69del, V70del, Y453F, I692V and M1229I. BioProject PRJNA716271, Sequencing of SARS-CoV-2 Isolates from BEI Resources, has been published on the NCBI website. The sequences from the BEI Resources SARS-CoV-2 isolates included in the project have been deposited into GenBank (SRA: SRP312598) and the sequence for SARS-CoV-2, isolate hCoV-19/Denmark/DCGC-3024/2020 (NR-53953), is available (SAMN18527800).
Each vial contains approximately 0.5 mL of cell lysate and supernatant from Cercopithecus aethiops kidney epithelial cells with human signaling lymphocytic activation molecule (hSLAM) infected with SARS-CoV-2, isolate hCoV-19/Denmark/DCGC-3024/2020.
Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), isolate hCoV-19/Denmark/DCGC-3024/2020 (also referred to as SARS-CoV-2, isolate hCoV-19/hu/DK/CL-5/1; Please note that the depositor’s original strain designation was used on the product label.) was isolated from a human who was exposed to a COVID-19 infected mink in Northern Jutland, Denmark on October 5, 2020.
Note: Genome sequence information is provided on the Certificate of Analysis and includes an analysis of all sequence variations observed for each lot.
Under the nomenclature system introduced by GISAID (Global Initiative on Sharing All Influenza Data), SARS-CoV-2, isolate hCoV-19/Denmark/DCGC-3024/2020 is assigned lineage B.1.1.298 and GISAID clade GR using Phylogenetic Assignment of Named Global Outbreak LINeages (PANGOLIN) tool. The complete genome of SARS-CoV-2, isolate hCoV-19/Denmark/DCGC-3024/2020 has been sequenced (GISAID: EPI_ISL_616802). The following mutations are present in the clinical isolate: Spike D614G, Spike H69del, Spike I692V, Spike M1229I, Spike V70del, Spike Y453F, N (Nucleocapsid protein) G204R, N R203K, N S194L, NSP1 (Non-structural protein 1) M85del, NSP3 (Non-structural protein 3) H182Y, NSP3 N1263del, NSP12 (Non-structural protein 12) P323L, NSP12 T739I, NSP15 (Non-structural protein 15) T112I. SARS-CoV-2, isolate hCoV-19/Denmark/DCGC-3024/2020 is a mink-associated SARS-CoV-2 Cluster 5 (also referred to as ΔFVI-spike) virus defined by the following Spike mutations: H69del, V70del, Y453F, I692V and M1229I. BioProject PRJNA716271, Sequencing of SARS-CoV-2 Isolates from BEI Resources, has been published on the NCBI website. The sequences from the BEI Resources SARS-CoV-2 isolates included in the project have been deposited into GenBank (SRA: SRP312598) and the sequence for SARS-CoV-2, isolate hCoV-19/Denmark/DCGC-3024/2020 (NR-53953), is available (SAMN18527800).
Each vial contains approximately 0.5 mL of cell lysate and supernatant from Cercopithecus aethiops kidney epithelial cells with human signaling lymphocytic activation molecule (hSLAM) infected with SARS-CoV-2, isolate hCoV-19/Denmark/DCGC-3024/2020.
主要内容
此项目的每个订单数量限制为1.此商品每年可订购两次.此限制的订单将在发货前发送到NIAID批准.
严重急性呼吸综合征相关的冠状病毒2(SARS-COV-2),分离HCOV-19 /丹麦/ DCGC-3024/2020(也称为SARS-COV-2,分离HCOV-19 / HU / DK / CL- 5/1; 请注意,存档仪的原始应变名称用于产品标签上使用.)从暴露于北部的Covid-19受感染的水貂的人类中分离出来Jutland,丹麦10月5日2020年.
注意:基因组序列信息在分析证书上提供,并且包括对每个批次观察到的所有序列变化的分析.
根据GISAID引入的命名系统(全球共享所有流感数据的计划),SARS-COV-2,隔离HCOV-19 /丹麦/ DCGC-3024/2020使用系统发育分配分配谱系B.1.1.298和GISAID CLADE GR命名为全球爆发谱系(Pangolin)工具.已经测序了SARS-COV-2的完整基因组,隔离HCOV-19 /丹麦/ DCGC-3024/2020(GISAID:EPI_ISL_616802).临床分离物中存在以下突变:Spike D614G,Spike H69Del,Spike I692V,Spike M1229i,Spike V70Del,尖峰Y453F,N(核衣壳蛋白)G204R,N R203K,N S194L,NSP1(非结构蛋白1)M85DEL ,NSP3(非结构蛋白3)H182Y,NSP3 N1263DEL,NSP12(非结构蛋白12)P323L,NSP12 T739i,NSP15(非结构蛋白15)T112i. SARS-COV-2,隔离HCOV-19 /丹麦/ DCGC-3024/2020是由以下尖峰突变定义的水貂相关的SARS-COV-2簇5(也称为ΔFVI-钉)病毒:H69DEL,V70DEL ,y453f,i692v和m1229i. bioproject prjna716271 ,
SARS-COV-2的测序来自BEI资源,已发表于
NCBI网站.来自BEI资源SARS-COV-2分离的序列
该项目中已包含在GenBank(SRA:)
和SARS-COV-2的序列,隔离HCOV-19 /丹麦/ DCGC-3024/2020(NR-53953)是
可用( samn18527800 ).
每个小瓶含有大约0.5ml的细胞裂解物和来自寒霉菌的肾上皮细胞,具有人的信号传导淋巴细胞活化分子(Hslam)感染SARS-COV-2,分离HCOV-19 /丹麦/ DCGC- 3024/2020.
厂牌介绍
BEI Resources 由美国国家过敏和传染病研究所 ( NIAID )成立,旨在为研究 A、B 和 C 类优先病原体、新兴传染病病原体、非病原微生物和其他相关微生物材料提供试剂、工具和信息到研究界。BEI Resources 获取、验证和生产科学家进行基础研究和开发改进的诊断测试、疫苗和疗法所需的试剂。通过将这些功能集中在 BEI Resources 中,可以监控科学界对这些材料的访问和使用,并确保试剂的质量控制。
除了为传染病界提供材料外,BEI Resources 还鼓励和支持研究人员和机构的材料存放。使用 BEI Resources存放材料对研究人员和研究社区有许多优势,包括安全存储、社区访问和分发;同时保护存款人的知识产权。只要有需要,BEI 资源库将作为研究人员的资源进行维护。您在 BEI Resources 的存款是一项有助于未来研究的长期投资。
BEI Resources 自 2003 年起由美国典型培养物保藏中心 (ATCC) 根据合同管理。2016 年 5 月, ATCC获得了一份为期七年的继续管理 BEI Resources的合同。合同范围已扩大到更全面的研究目录材料,包括由其他政府支持的研究项目存放的材料,将提供给生物防御和新兴传染病科学界。真菌、寄生虫、载体和其他相关材料已添加到现有的细菌、病毒和毒素试剂中,涵盖 NIAID A、B 和 C 类优先病原体和 NIAID 指定的新发传染病病原体和生物。
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