NR-19818问号钩端螺旋体,M776,毛皮突变体(SerovarManilae)(细菌）

NR-19818??Leptospira interrogans, M776, fur Mutant (Serovar Manilae)(Bacteria)|Leptospira interrogans|M776, fur Mutant (Serovar Manilae)|-60°C or colder|B AdlerAcknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Leptospira interrogans, Strain M776, fur Mutant (Serovar Manilae), NR-19818."|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.Leptospira interrogans (L. interrogans), strain M776 (serovar Manilae) is a transposon mutant of wild-type strain L495 created by disruption of the fur gene (la1857), which encodes the ferric uptake regulator protein Fur, in strain L495.L. interrogans, strain M776 (serovar Manilae) is 8-fold more resistant to hydrogen peroxide and expression of the katE gene is upregulated 2.4-fold compared to the wild type, and virulence is not attenuated in a hamster model of infection. The whole genome shotgun sequence of L. interrogans, strain M776 (serovar Manilae) is available (GenBank: AHPT00000000).Each vial contains approximately 0.5 mL of bacterial culture in Ellinghausen-McCullough-Johnson-Harrison (EMJH) Medium supplemented with 2.5% DMSO.