产品图片
货号/SKU
MRA-479A
货号/规格
EA
库存与交货期
3-8周
人民币价格
14000
试剂海关审批
A/B级风险物质只能直接使用人购买并持有实验室有效资质,其它询客服确认
国外采购
支持/部分限制一年内购买数量
厂牌
BEI Resources(ATCC)
产品基础信息
生物安全等级建议分类:美国、1
产品描述信息
MRA-479A?? Monoclonal Anti-Plasmodium falciparum Apical Membrane Antigen 1 (AMA1), Clone N3-2D9 (produced in vitro)(Monoclonal Antibodies)|Plasmodium falciparum|Monoclonal Anti-Plasmodium falciparum Apical Membrane Antigen 1 (AMA1), Clone N3-2D9 (produced in vitro)|-20°C or colder|CA LongAcknowledgment for publications should read "The following reagent was obtained through BEI Resources, NIAID, NIH: Monoclonal Anti-Plasmodium falciparum Apical Membrane Antigen 1 (AMA1), Clone N3-2D9 (produced in vitro), MRA-479A, contributed by Carole A. Long."|Quantity limit per order for this item is 1. This item can be ordered twice a year. Orders over this limit will be sent to NIAID for approval before shipment.
Antibody Class: IgG1κ, IgG2aκ
The hybridoma from which MRA-479 was derived is reported to produce antibody of the IgG1 subclass, but MRA-479 occasionally contains both IgG1κ and IgG2aκ probably because of a mixed hybridoma clone. However, the functional activity of this antibody preparation has been confirmed (see below).
Monoclonal antibody prepared against the apical membrane antigen 1 (AMA1) of Plasmodium falciparum (P. falciparum) was purified from supernatants obtained from mouse N3-2D9 hybridoma. The N3-2D9 monoclonal antibody is specific for the AMA1 of P. falciparum.
Monoclonal antibody N3-2D9 is reported to function in western blot and immunofluorescence assays, and have a < 30% growth inhibitory effect on P. falciparum, strain FVO.
Each vial contains approximately 100 ?L (lot 70026314) or 250 ?L (lot 3361174) of purified monoclonal antibody in PBS pH 7.2.
Antibody Class: IgG1κ, IgG2aκ
The hybridoma from which MRA-479 was derived is reported to produce antibody of the IgG1 subclass, but MRA-479 occasionally contains both IgG1κ and IgG2aκ probably because of a mixed hybridoma clone. However, the functional activity of this antibody preparation has been confirmed (see below).
Monoclonal antibody prepared against the apical membrane antigen 1 (AMA1) of Plasmodium falciparum (P. falciparum) was purified from supernatants obtained from mouse N3-2D9 hybridoma. The N3-2D9 monoclonal antibody is specific for the AMA1 of P. falciparum.
Monoclonal antibody N3-2D9 is reported to function in western blot and immunofluorescence assays, and have a < 30% growth inhibitory effect on P. falciparum, strain FVO.
Each vial contains approximately 100 ?L (lot 70026314) or 250 ?L (lot 3361174) of purified monoclonal antibody in PBS pH 7.2.
主要内容
此项目的每个订单数量限制为1.此商品每年可订购两次.此限制的订单将在发货前发送到NIAID批准.
抗体类:Igg1κ,Igg2aκ
据报道,衍生MRA-479的杂交瘤以产生IgG1亚类的抗体,但MRA-479偶尔含有IgG1κ和IgG2aκ,可能是因为混合杂交瘤克隆.然而,已经证实了该抗体制剂的功能活性(参见下文)
从小鼠N3-2D9杂交瘤中获得的上清液中纯化含有疟原虫(P. falciparum)的顶端膜抗原1(AMA1)的单克隆抗体. N3-2D9单克隆抗体是 P的AMA1的特异性. Falciparum .
据报道单克隆抗体N3-2D9在蛋白质印迹和免疫荧光测定中起作用,并且具有&lt; 30%的生长抑制作用对 p. Falciparum ,菌株FVO.
每个小瓶在PBS pH 7.2中含有约100μl(批量70026314)或250μL(批量3361174)的纯化的单克隆抗体.
厂牌介绍
BEI Resources 由美国国家过敏和传染病研究所 ( NIAID )成立,旨在为研究 A、B 和 C 类优先病原体、新兴传染病病原体、非病原微生物和其他相关微生物材料提供试剂、工具和信息到研究界。BEI Resources 获取、验证和生产科学家进行基础研究和开发改进的诊断测试、疫苗和疗法所需的试剂。通过将这些功能集中在 BEI Resources 中,可以监控科学界对这些材料的访问和使用,并确保试剂的质量控制。
除了为传染病界提供材料外,BEI Resources 还鼓励和支持研究人员和机构的材料存放。使用 BEI Resources存放材料对研究人员和研究社区有许多优势,包括安全存储、社区访问和分发;同时保护存款人的知识产权。只要有需要,BEI 资源库将作为研究人员的资源进行维护。您在 BEI Resources 的存款是一项有助于未来研究的长期投资。
BEI Resources 自 2003 年起由美国典型培养物保藏中心 (ATCC) 根据合同管理。2016 年 5 月, ATCC获得了一份为期七年的继续管理 BEI Resources的合同。合同范围已扩大到更全面的研究目录材料,包括由其他政府支持的研究项目存放的材料,将提供给生物防御和新兴传染病科学界。真菌、寄生虫、载体和其他相关材料已添加到现有的细菌、病毒和毒素试剂中,涵盖 NIAID A、B 和 C 类优先病原体和 NIAID 指定的新发传染病病原体和生物。
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