- 4 次围观
产品图片
产品别名
货号/SKU
EF0013
货号/规格
100ug
库存与交货期
4-6 周
人民币价格
10390
试剂海关审批
使用人负责A/B风险申请资质
国外采购
支持/部分需签MTA
厂牌
Kerafast, Inc.
品牌
产品基础信息
From the laboratory of David L. Paul, PhD, Harvard University.
产品描述信息
Product Type: | Antibody |
Antigen: | Connexin-32, Gap junction beta-1 protein, Cx32, Gjb1 |
Accession ID: | NM_017251.2 |
Molecular Weight: | 32,007 Da |
Isotype: | IgG |
Clonality: | Monoclonal |
Clone Name: | M12.13 |
Reactivity: | Mouse, rat, human |
Immunogen: | isolated rat hepatocyte gap junctions |
Species Immunized: | Mouse |
Epitope: | On cytoplasmic surface, likely between residues 95-125 |
Purification Method: | Serum separation from whole blood |
Buffer: | Whole serum |
Tested Applications: | IHC (acetone or unfixed tissues recommended. Epitope is internal, paraffin sections are untested. Works with lightly formaldehyde-fixed tissue). WB (Detects a 27 kDa Connexin 32 polypeptide in blots of rat hepatocyte gap junctions and an additional 47 kDa band corresponding to aggregates). |
Storage: | -80C long term, 4C short term |
Shipped: | Dry ice |
产品安全信息
Goodenough DA, Paul DL, Jesaitis L. 1988. Topological distribution of two Connexin32 antigenic sites in intact and split rodent hepatocyte gap junctions. J.Cell Biol. 107:1817-1824. Hamzei-Sichani F, Davidson KG, Yasumura T, Janssen WG, Wearne SL, Hof PR, Traub RD, Gutiérrez R, Ottersen OP, Rash JE. Mixed Electrical-Chemical Synapses in Adult Rat Hippocampus are Primarily Glutamatergic and Coupled by Connexin-36. Front Neuroanat. 2012 May 15;6:13. Rela L, Bordey A, Greer CA. Olfactory ensheathing cell membrane properties are shaped by connectivity. Glia. 2010 Apr 15;58(6):665-78. doi: 10.1002/glia.20953. Fowler SL, McLean AC, Bennett SA. Tissue-specific cross-reactivity of connexin32 antibodies: problems and solutions unique to the central nervous system. Cell Commun Adhes. 2009 Dec;16(5-6):117-30. Rash JE, Olson CO, Pouliot WA, Davidson KG, Yasumura T, Furman CS, Royer S, Kamasawa N, Nagy JI, Dudek FE. Connexin36 vs. connexin32, "miniature" neuronal gap junctions, and limited electrotonic coupling in rodent suprachiasmatic nucleus. Neuroscience. 2007 Oct 26;149(2):350-71. Epub 2007 Jul 21. Rash JE, Olson CO, Davidson KG, Yasumura T, Kamasawa N, Nagy JI. Identification of connexin36 in gap junctions between neurons in rodent locus coeruleus. Neuroscience. 2007 Jul 29;147(4):938-56. Epub 2007 Jul 2. Fischer R, Reinehr R, Lu TP, Schönicke A, Warskulat U, Dienes HP, Häussinger D. Intercellular communication via gap junctions in activated rat hepatic stellate cells. Gastroenterology. 2005 Feb;128(2):433-48. Rash JE, Pereda A, Kamasawa N, Furman CS, Yasumura T, Davidson KG, Dudek FE, Olson C, Li X, Nagy JI. High-resolution proteomic mapping in the vertebrate central nervous system: close proximity of connexin35 to NMDA glutamate receptor clusters and co-localization of connexin36 with immunoreactivity for zonula occludens protein-1 (ZO-1). J Neurocytol. 2004 Jan;33(1):131-51. Alvarez-Maubecin V, Garcia-Hernandez F, Williams JT, Van Bockstaele EJ. Functional coupling between neurons and glia. J Neurosci. 2000 Jun 1;20(11):4091-8. Day WE, Bowen JA, Barhoumi R, Bazer FW, Burghardt RC. Endometrial connexin expression in the mare and pig: evidence for the suppression of cell-cell communication in uterine luminal epithelium. Anat Rec. 1998 Jul;251(3):277-85.If you publish research with this product, please let us know so we can cite your paper.
主要内容
将该小鼠IgG单克隆抗体升高针对分离的大鼠肝细胞间隙连接点,并识别人,小鼠和大鼠间隙结β-1蛋白(Connexin-32).highlights:在细胞质表面上识别人,小鼠和大鼠Connexin-32(残留物95-125)适用于Western印迹和免疫组织化学Connexins是跨跨越蛋白质,其组装以形成促进离子和细胞之间的小分子的转移的间隙结通道。一个间隙结由一组紧密包装的跨膜通道,连接群,通过该跨越式跨越子,通过该跨越的材料从一个电池扩散到邻近的细胞。从哈佛大学博士博士博士的实验室。
厂牌介绍
关于Kerafast Inc.
Kerafast 是一家位于波士顿的试剂公司,其主要使命是为QuanQiu科学界提供易于使用的独特实验室研究工具。我们的产品组合包括细胞系、抗体、小分子、染料等,其中许多在其他地方无法获得。自 2011 年成立以来,来自全球 190 多个机构的研究人员通过我们的在线平台提供了他们的创新试剂,无需通过传统的材料转让协议流程即可快速获取材料。
我们处理提供实验室的所有销售和运输物流,并从每次销售中返还丰厚的特许权使用费。因此,我们帮助提供实验室节省时间和资源,同时为进一步研究提供额外资金。采购科学家可以更轻松地发现和获取其他地方通常无法获得的独特试剂,同时还可以资助其他研究人员的工作。这创建了一个QuanQiu科学家社区,他们贡献和获取Reagent for the Greater Good,以加速他们自己的研究以及整体科学进步。
2018 年,Kerafast 与Absolute Antibody合并,后者是一家总部位于英国的公司,其愿景是为所有研究人员提供重组抗体技术。此次合并将两家公司聚集在一起,共同致力于改善科学界可用的研究工具的选择。
品牌标识
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