16-14-012621

MW: 37,000**
**Azurocidin is highly glycosylated, which causes the protein to show a lower molecular weight by SDS-PAGE than that stated of 37kDa.
Extinction Coefficient: 0.51

Salt-free lyophilized solid.

Storage:

Bulk Qty Available.

The gene for azurocidin is located on the short arm of chromosome 19 and is in a cluster with the genes for proteinase 3 and elastase. All three proteins are serine protease homologues; azurocidin, however, lacks enzymatic activity. The importance of azurocidin is its role as a multifunctional inflammatory mediator. It has antimicrobial activity, binds endotoxin and is chemotactic for monocytes.

Purity: >=95% by SDS-PAGE

Prepared from whole blood shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Lab products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research or further manufacturing use only.

Product Citation:

Zimmer M, Medcalf RL, Fink TM, Mattman C, Lichter P, and Jenne DE. 1992. Proc. Natl. Acad. Sci. USA 89, 8215. Pereira HA. 1995. J Leukoc Biol. 57, 805.

O'Flynn, J., K. O. Dixon, Faber Krol, M. R. Daha, and C. van Kooten. "Myeloperoxidase Directs Properdin-Mediated Complement Activation."?Journal of Innate Immunity?(2013).

Brandt K, Grunler J, Brismar K, Wang J
Effects of IGFBP-1 and IGFBP-2 and their fragments on migration and IGF-induced proliferation of human dermal fibroblasts.
Growth Horm IGF Res. 2015 Feb;25(1):34-40. doi: 10.1016/j.ghir.2014.11.001. Epub 2014 Nov 8.

MW: 37,000**
**Azurocidin is highly glycosylated, which causes the protein to show a lower molecular weight by SDS-PAGE than that stated of 37kDa.
Extinction Coefficient: 0.51

Salt-free lyophilized solid.

Storage:

Bulk Qty Available.

The gene for azurocidin is located on the short arm of chromosome 19 and is in a cluster with the genes for proteinase 3 and elastase. All three proteins are serine protease homologues; azurocidin, however, lacks enzymatic activity. The importance of azurocidin is its role as a multifunctional inflammatory mediator. It has antimicrobial activity, binds endotoxin and is chemotactic for monocytes.

Purity: >=95% by SDS-PAGE

Prepared from whole blood shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.

Lab products are laboratory reagents and are not to be administered to humans or used for any drug purpose. For research or further manufacturing use only.

Product Citation:

Zimmer M, Medcalf RL, Fink TM, Mattman C, Lichter P, and Jenne DE. 1992. Proc. Natl. Acad. Sci. USA 89, 8215. Pereira HA. 1995. J Leukoc Biol. 57, 805.

O'Flynn, J., K. O. Dixon, Faber Krol, M. R. Daha, and C. van Kooten. "Myeloperoxidase Directs Properdin-Mediated Complement Activation."?Journal of Innate Immunity?(2013).

Brandt K, Grunler J, Brismar K, Wang J
Effects of IGFBP-1 and IGFBP-2 and their fragments on migration and IGF-induced proliferation of human dermal fibroblasts.
Growth Horm IGF Res. 2015 Feb;25(1):34-40. doi: 10.1016/j.ghir.2014.11.001. Epub 2014 Nov 8.