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Synonyms: ACT, AACT, SERPINA3, Alpha 1-ACT, A1ACT
MW: 64,000
Extinction Coefficient: 0.6
Lyophilized from 20 mM Tris, pH 7.4, with 150 mM NaCl
Storage:
Buy Alpha 1 Antichymotrypsin from human plasma direct from the manufacturer. Same day shipping for this laboratory reagent.
An acute-phase plasma protein found at 45 mg per 100 ml. ACT functions as a specific inhibitor of chymotrypsin-like serine proteases. Clinically, it is elevated in inflammatory conditions, some malignancies, Crohn's disease, ulcerative colitis, and burn injuries. The PSA-ACT complex level is considered a biomarker for prostate cancer.
Purity: >=95% by SDS-PAGE
Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Lab products are laboratory reagents and are not to be administered to humans or used for any drug purpose.
For research use or for use in further manufacturing.
Product Citation:
Aldredge, Danielle, Hyun Joo An, Ning Tang, Keith Waddell, and Carlito B. Lebrilla. "Annotation of a serum N-glycan library for rapid identification of structures."Journal of proteome research 11, no. 3 (2012): 1958-1968.
Zhu, Lei, Sari J??maa, Taija M. af H?llstr?m, Marikki Laiho, Anna Sankila, Stig Nordling, Ulf‐H?kan Stenman, and Hannu Koistinen. "PSA forms complexes with α1‐antichymotrypsin in prostate." The Prostate 73, no. 2 (2013): 219-226.