Non-Invasive Assessment of Embryo Physiology

root 提交于 周三, 09/02/2026 - 18:00

Methods Mol Biol. 2026;3038:147-170. doi: 10.1007/978-1-0716-5292-3_10.

ABSTRACT

Through miniaturisation of enzymatic reactions, microfluorescence analyses enable the non-invasive assessment of embryo metabolism. Nutrient concentrations in embryo culture medium are quantified by ultramicrofluorescence (UMF) techniques, which utilise specialised constriction pipettes and a fluorescent microscope coupled with a photomultiplier tube and photometer, to quantitate nutrient levels in nanolitre or picolitre volumes of spent media. Here, the non-invasive method for analysis of embryo metabolism utilising spent culture media and UMF is described.

PMID:42681383 | DOI:10.1007/978-1-0716-5292-3_10