JBRA Assist Reprod. 2025 Dec 22. doi: 10.5935/1518-0557.20250182. Online ahead of print.
ABSTRACT
This case report describes a healthy live birth following in vitro fertilization (IVF) resulting from the transfer of a euploid embryo derived from a tri-pronuclear zygote (3PN), along with a review of related literature. The case occurred at a private IVF center. It involves a nulliparous 29-year-old woman with abnormal ovarian reserve and male factor infertility who underwent IVF. Preimplantation genetic testing for aneuploidy and noninvasive prenatal testing with cell-free fetal DNA indicated normal ploidy. This report provides evidence that transferring a euploid embryo from an abnormally fertilized oocyte (tri-pronuclear zygote) can lead to a clinical pregnancy and a healthy live birth.
PMID:41428722 | DOI:10.5935/1518-0557.20250182