Cell Stem Cell. 2025 Oct 2;32(10):1477-1478. doi: 10.1016/j.stem.2025.08.016.
ABSTRACT
Two recent studies from the Silva and Hanna groups optimized chemical induction and culture conditions to derive extraembryonic lineages directly from embryonic stem cells (ESCs) without transgenes, enabling mouse stem cell-based embryo models (SCBEMs) to reproducibly advance to the E8.5-E8.75 stage.
PMID:41043397 | DOI:10.1016/j.stem.2025.08.016
来源出处
Building the start: Unlocking advanced stem cell-based embryo models
https://pubmed.ncbi.nlm.nih.gov/41043397/?utm_source=Other&utm_medium=rss&utm_c…