Evaluation of an Ipsilateral Uterine Horn Resection and Ovariectomy Surgical Model in Gilts for Embryo Collection

root 提交于 周四, 08/28/2025 - 18:00

Animals (Basel). 2025 Aug 12;15(16):2366. doi: 10.3390/ani15162366.

ABSTRACT

Minimizing the risk of disease transmission, disseminating superior genetics, and reducing transportation costs are recognized advantages of embryo biotechnologies. These advantages make the development of a minimally invasive and repeatable procedure in pigs enticing, but simultaneously magnify the anatomical constraints. For decades, the swine industry has struggled to establish a universal procedure to collect pre-implantation embryos from pigs due to their long and convoluted uterine horns (UHs). Thus, the objectives were to evaluate the benefits of employing a transitional surgical model by shortening UH tissue using a 40 cm ipsilateral resection and assess the compensatory ovulatory response following an ovariectomy. The surgery was deemed successful as the UH was resected and the contralateral UH was fully ligated. The dam- and sire-line gilts exhibited ovarian hypertrophy between surgery and slaughter on the remaining ovary, illustrated by an increase in the number of corpora lutea (13.4 and 3.0 vs. 27.2 and 12; p p

PMID:40867695 | PMC:PMC12383179 | DOI:10.3390/ani15162366