- 2 次围观
Zhonghua Nan Ke Xue. 2024 Aug;30(8):722-729.
ABSTRACT
OBJECTIVE: To investigate the effects of sperm DNA fragmentation index (DFI) on embryonic development and live birth outcomes of in vitro fertilization-fresh embryo transfer (IVF-ET).
METHODS: We selected 947 cases of IVF-ET due to female factors from June 2015 to December 2020 and, according to the DFI, divided them into a low- (DFI
RESULTS: The patients in the medium- and high-DFI groups had a significantly older age than those in the low-DFI group. There were statistically significant differences among the three groups in the baseline percentages of progressively motile sperm, non-progressively motile sperm and immotile sperm, and total sperm motility and progressive sperm motility before IVF (P
CONCLUSION: High DFI significantly affects sperm motility. The DFI level after semen treatment is negatively correlated with sperm concentration, total sperm count and fertilization rate, but does not affect embryo quality and pregnancy outcome.
PMID:40778798